Results 141 to 150 of about 753,617 (295)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Different inhibitory concentrations (IC) of cisplatin in HeLa, SiHa shREV3L cells and control cells.
, 2015 IC30, 30% inhibitory concentration of cisplatin; IC50, 50% inhibitory concentration of cisplatin; IC70, 70% inhibitory concentration of cisplatin ...
Gong Yang (216381) +8 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
四川大学学报. 自然科学版, 2018 AChE was purified by affinity chromatography from Locusta migratoria head. The purification factors and yields were 474.81fold and 28.93%, respectively. The molecular weight of the purified enzyme was 67.22kDa, measured by SDSPAGE.
DENG Yuan-Jie +5 more
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
, 2015 1MIC50 corresponds to the lowest concentration of each test agent that inhibited growth in 50% of bacterial isolates screened.2MBC50 corresponds to the lowest concentration of each test agent that killed 50% of bacterial isolates screened.Minimum ...
G. Kenitra Hammac (680867) +6 more
core +1 more source
Contribution à l’étude de l’activité antibactérienne du miel naturel d’origine marocaine
Revue Marocaine des Sciences Agronomiques et Vétérinaires, 2016 Eight samples of natural Moroccan honeys were tested for their antimicrobial effect, at the concentrations of 100, 75, 50 and 25%, on three bacterial strains, Escherichia coli, Staphylococcus aureus and Salmonella spp.
O. BELHAJ, I. EL ABBADI, T. OUCHBANI
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
, 2019 Objective: Periodontal abscess is an inflammatory process that occurs due to a localized bacterial infection involving deeper periodontal structures and may occur acutely or chronically.
POERNOMO, HENDRI, HARYANI, DEWI
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source