Results 71 to 80 of about 7,131,135 (287)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2015 BACKGROUND AND OBJECTIVE In traditional medicine, pomegranate is used for the treatment of intestinal worms and diarrhea. This study aimed to examine the antibacterial activities of pomegranate extracts on biofilm structures and planktonic forms of six ...
Mehdi Hassanshahian, Zinab Mohsenipour
doaj
Half-maximal inhibitory concentration (IC50) values (nM) of MKP101 for human kinases.
, 2015 *The data, except for that of EGFR, are the values reported in reference [31].Half-maximal inhibitory concentration (IC50) values (nM) of MKP101 for human kinases.
Jiho Song (799714) +7 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Interdental Jurnal Kedokteran Gigi (IJKG)Introduction: Necrotic teeth can be maintained with root canal treatment, through three critical stages, namely preparation, sterilization, and filling. Sterilization is one of the critical stages that must be carried out during treatment, and it aims to eliminate as many pathogenic microorganisms as possible through irrigation and medicine.
Putu Rusmiany +2 more
openaire +1 more source
Eugenol minimum inhibitory concentration.
, 2016 Eugenol minimum inhibitory concentration.
Amanda Teixeira de Melo (3190281) +11 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Compounds from Extracts with Toxicity against the Fish Pathogenic Bacterium
Natural Product Communications, 2016 The pond-raised channel catfish (Ictalurus punctatus ) industry in the United States of America can incur losses of over a $100 million annually due to bacterial diseases including columnaris disease caused by Flavobacterium columnare.
Kevin K. Schrader +3 more
doaj +1 more source
Analytical ChemistryThe half-maximal inhibitory concentration (IC50) is a critical pharmacological parameter used to quantify a drug's potency in inhibiting biological functions. In this study, we present a novel strategy to evaluate the cytotoxicity of anticancer drugs on CL1-0 and A549 lung cancer cells, Huh-7 liver cancer cells, and MCF-7 breast cancer cells using ...
Hsien-San Hou +4 more
openaire +2 more sources
, 2018 Medicinal plants are widely used for the treatment of different diseases. The purpose of this study is to observe the antibacterial and minimum inhibitory concentration of ethanolic leaves extract of three medicinal plants (Psidium guajava, Ficus ...
KV Hridhya +4 more
core +1 more source