Results 61 to 70 of about 753,617 (295)

Summary of Drug Titrations Showing 50% Inhibitory Concentration, IC₅₀, in Breast Cancer Cell Lines Treated with Paclitaxel and Analogs.

, 2015
The IC50 values are given in nM. Values and errors (SE) shown are representative of n = 3 independent experiments.* P < 0.05 determined for IC50 for each analog relative to paclitaxel.Summary of Drug Titrations Showing 50% Inhibitory Concentration, IC50,
Richard F. Ludueña (751489), Sambasivarao Damaraju (102523), Ahmed T. Ayoub (747972), Carol E. Cass (102519), Mariusz Klobukowski (747973), Jack A. Tuszynski (160860), Marc St. George (318231), Philip Winter (291799), Asok Banerjee (751487), Cassandra D. M. Churchill (751488)   +9 more
core   +1 more source

The effect of ethanol extract of Glycyrrhiza uralensis on the voltage-gated sodium channel subtype 1.4

Journal of Pharmacological Sciences, 2018
To investigate the inhibitory effect of Glycyrrhiza uralensis (G. uralensis) and its monomeric compounds on Nav1.4 voltage-gated sodium channels (VGSCs) and analyze the relationship between the content of its marker compounds and the inhibitory rate ...
Guangwei Zhu, Shengjun Ma, Xiwen Li, Peng Zhang, Lin Tang, Lijuan Cao, Aoxue Liu, Toru Sugita, Takehisa Tomoda   +8 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Effect of ingredient concentration on inhibitory effects of serine protease activity of TMPRSS2.

, 2021
The dose-response inhibitory effects of TMPRSS2 serine protease activity by (A) Sodium dodecyl sulfate, (B) Sodium tetradecene sulfonate, (C) Copper gluconate, (D) Tranexamic acid, (E) Sodium N-lauroyl-N-methyltaurate, (F) Sodium N-lauroylsarcosinate ...
Kota Tsutsumi (11450410), Riho Tateyama-Makino (11450404), Keiichi Tsukinoki (11450413), Mari Abe-Yutori (11450407), Kei Kurita (6158435), Yukio Yamamoto (365626), Taku Iwamoto (3235668), Motonori Tsuji (2715355), Eiji Nishinaga (3004290), Satoru Morishita (818840)   +9 more
core   +1 more source

Phenylpyrazalopyrimidines as Tyrosine Kinase Inhibitors: Synthesis, Antiproliferative Activity, and Molecular Simulations

Molecules, 2020
N1-(α,β-Alkene)-substituted phenylpyrazolopyrimidine derivatives with acetyl and functionalized phenyl groups at α- and β-positions, respectively, were synthesized by the reaction of 3-phenylpyrazolopyrimidine (PhPP) with bromoacetone, followed by a ...
Bhupender S. Chhikara, Sajda Ashraf, Saghar Mozaffari, Nicole St. Jeans, Dindyal Mandal, Rakesh Kumar Tiwari, Zaheer Ul-Haq, Keykavous Parang   +7 more
doaj   +1 more source

Activity of propolis from Mexico on the proliferation and virulence factors of Candida albicans

BMC Microbiology, 2023
Background This research evaluated the anti-Candida albicans effect of Mexican propolis from Chihuahua. Chemical composition of the ethanolic extract of propolis was determined by GC-MS, HPLC-DAD, and HPLC-MS. The presence of anthraquinone, aromatic acid,
Mario Rodriguez-Canales, Yoli Mariana Medina-Romero, Marco Aurelio Rodriguez-Monroy, Uriel Nava-Solis, Sandra Isabel Bolaños-Cruz, Maria Jimena Mendoza-Romero, Jorge E. Campos, Ana Bertha Hernandez-Hernandez, Yolanda I. Chirino, Tonatiuh Cruz-Sanchez, Carlos Gerardo Garcia-Tovar, Maria Margarita Canales-Martinez   +11 more
doaj   +1 more source

Study on α-glucosidase inhibitory activity of 40 kinds of vegetables, tubers, and fruits in An Giang

Vietnam Journal of Science, Technology and Engineering, 2022
A study on the α-glucosidase inhibitory activity of 40 kinds of vegetables, tubers, and fruits found in the An Giang province was conducted. The results indicated that all 40 extracted samples displayed α-glucosidase inhibitory activity at a ...
Thi-My-Linh Lam, Minh-Tuan Le, Manh-Ha Bui   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Inhibitory effect of enterocin GL on Listeria monocytogenes biofilm [PDF]

Zhongguo niangzao
To investigate the inhibitory effect of enterocin GL on Listeria monocytogenes biofilm formation, the sub-lethal concentration and its bactericidal effect were determined, viable cell counts in biofilm, metabolic activity, motility, and extracellular ...
TAO Lin, LEI Yao, LI Yong, JI Zimu, LIU Weihang, DU Lihui
doaj   +1 more source

Synthesis and spectroscopic study of novel mixed ligand formula “Artemisinin/Zn” and assessment of its inhibitory effect against “SARS-CoV-2″

Heliyon, 2023
Background: Herein, a newly synthesised mixed ligand artemisinin/zinc (Art/Zn) is chemically characterised and examined against SARS-CoV-2. Methods: The synthesised complex was thoroughly characterised using various spectroscopic methods (FT-IR, UV and ...
Fawziah A. Al-Salmi, Samy M. El-Megharbel, Reham Z. Hamza   +2 more
doaj   +1 more source