Results 11 to 20 of about 753,617 (295)

Anti-malarial investigation of Acorus calamus, Dichapetalum gelonioides, and Leucas aspera on Plasmodium falciparum strains

Journal of Infection in Developing Countries, 2022
Introduction: Malaria is a significant global health concern and adversely affects people in developing countries including Bangladesh. The causative agent Plasmodium falciparum is resistant to several currently available anti-malarial drugs, such as ...
Md Fahad Zamil, Saiful Arefeen Sazed, Muhammad Riadul Haque Hossainey, Anik Biswas, Mohammad Shafiul Alam, Hamida Khanum, Priyanka Barua   +6 more
doaj   +1 more source

Assessing Anti-malaria Effect of Naja Naja Oxiana Snake Venom by Real-time Polymerase Chain Reaction Method

Complementary Medicine Journal of Faculty of Nursing and Midwifery, 2021
Objective: Malaria is one of the most important parasitic diseases and one of the important health issues especially in tropical and subtropical countries.
Fatemeh Hajialiani, Sedigheh Sadeghi, Delavar Shahbazzadeh, Fatemeh Tabatabaie , Zahra Zamani   +4 more
doaj   +1 more source

Asymptomatic COVID-19 re-infection in a Japanese male by elevated half-maximal inhibitory concentration (IC50) of neutralizing antibodies [PDF]

Journal of Infection and Chemotherapy, 2021
"Re-infection" with COVID-19 is a growing concern; re-infection cases have reported worldwide. However, the clinical characteristics of SARS-CoV-2 re-infection, including the levels and role of anti-SARS-CoV-2 Spike protein IgG antibodies and the half-maximal concentration (IC50) of neutralizing antibodies remain unknown.Both the epidemiological and ...
Makoto Inada, Masahiro Ishikane, Mari Terada, Akihiro Matsunaga, Kenji Maeda, Kiyoto Tsuchiya, Kenji Miura, Yu Sairenji, Noriko Kinoshita, Mugen Ujiie, Satoshi Kutsuna, Yukihito Ishizaka, Hiroaki Mitsuya, Norio Ohmagari   +13 more
openaire   +2 more sources

Aktivitas Antibakteri Ekstrak Etanol Daun Harendong Bulu (Clidemia Hirta) asal Maluku terhadap Staphylococcus Aureus

JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan), 2022
Pleroma urvilleanum (Clidemia hirta) is a plant that is widely found in Maluku, which contains chemical compounds, including tannins (catechols and pyrogalotanins), dioxyanthraquinones, steroids, saponins, glycosides and phenols which of these contents ...
Aulia Debby Pelu, Jayanti Djarami
doaj   +1 more source

Evaluation of Antibacterial Properties and Cytotoxicity of Ethanolic Extract of Alhagi Maurorum [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2023
Background and Objective: Cervical cancer is the fourth most common cancer in the world. The most important issue in cancer treatment is the destruction of cancer cells in the presence of normal cells.
FS Motafeghi, M Shokrzadeh, H Mohammadi, Sh Shokrzadeh, H Razaghi   +4 more
doaj  

Estimation of Serum-Free 50-Percent Inhibitory Concentrations for Human Immunodeficiency Virus Protease Inhibitors Lopinavir and Ritonavir [PDF]

Antimicrobial Agents and Chemotherapy, 2004
ABSTRACTUsing measured free fraction and 50% inhibitory concentration (IC50) values for the human immunodeficiency virus protease inhibitors lopinavir (LPV) and ritonavir (RTV) in tissue culture media with various protein concentrations ranging from 5 to 50%, we estimated serum-free IC50values for each drug.
Dean, Hickman, Sudthida, Vasavanonda, George, Nequist, Lynn, Colletti, Warren M, Kati, Richard, Bertz, Ann, Hsu, Dale J, Kempf   +7 more
openaire   +2 more sources

Determination of Diarrhetic Shellfish Poison by Measuring 50% Acid Phosphatase Activity Inhibitory Concentration (APIC₅₀)

Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 1985
A practical determination of diarrhetic shellfish poison (DSP) was established by measuring the 50% acid phosphatase activity inhibitory concentration (APIC50) with Tetrahymena pyriformis, in place of the mouse lethal assay. That is, DSP was extracted with acetone and ether from the toxic hepatopancreas of scallops, and applied to a silicic acid column.
SHIRAKI, Koichi, NAKAYA, Ken-ichi, SUGITANI, Akira, YAMADA, Fujizo   +3 more
openaire   +3 more sources

Lower than expected maraviroc concentrations in cerebrospinal fluid exceed the wild-type CC chemokine receptor 5-tropic HIV-1 50% inhibitory concentration [PDF]

AIDS, 2012
To measure maraviroc total cerebrospinal fluid (CSF) concentrations and compare them with total and unbound plasma concentrations. Total maraviroc was measured by reverse-phase high-performance liquid chromatography with tandem mass spectrometry, whereas ultrafiltration was used for unbound maraviroc. Maraviroc was detected in all nine CSF/plasma pairs
David, Croteau, Brookie M, Best, Scott, Letendre, Steven S, Rossi, Ronald J, Ellis, David B, Clifford, Ann C, Collier, Benjamin B, Gelman, Justin C, McArthur, John Allen, McCutchan, Susan, Morgello, Igor, Grant   +11 more
openaire   +2 more sources

Experimental therapeutic assays of Tephrosia vogelii against Leishmania major infection in murine model: in vitro and in vivo

BMC Research Notes, 2017
Background Conventional targeted leishmanicidal chemotherapy has persistently remained prohibitive for most economically deprived communities due to costs, associated time to accessing health services and duration for successful treatment programme ...
Sylvia Naliaka Marango, Christopher Khayeka-Wandabwa, Judith Alice Makwali, Bernard Ngoitsi Jumba, Joseph K. Choge, Eric Onyango Adino, Christopher O. Anjili   +6 more
doaj   +1 more source

Inhibitory Potential of Synthetic Amino Acid Derivatives against Digestive Enzymes as Promising Hypoglycemic and Anti-Obesity Agents

Biomolecules, 2023
Over the last decades, the increased incidence of metabolic disorders, such as type two diabetes and obesity, has motivated researchers to investigate new enzyme inhibitors. In this study, the inhibitory effects of synthetic amino acid derivatives (PPC80,
Franciane Campos da Silva, Bruna Celeida Silva Santos, Pedro Pôssa de Castro, Giovanni Wilson Amarante, Orlando Vieira de Sousa   +4 more
doaj   +1 more source