Results 11 to 20 of about 7,131,135 (287)

The rapid analysis of fungal growth in the presence of inhibitory effects [PDF]

, 2011
For fungal contamination of foodstuffs, there are no fast, reliable, automated techniques to examine growth, nor have any predictive models been developed to describe the growth in the same way as for bacteria. Traditional plating methods can take 3 to
Williams, Tyson
core   +7 more sources

Asymptomatic COVID-19 re-infection in a Japanese male by elevated half-maximal inhibitory concentration (IC50) of neutralizing antibodies [PDF]

Journal of Infection and Chemotherapy, 2021
"Re-infection" with COVID-19 is a growing concern; re-infection cases have reported worldwide. However, the clinical characteristics of SARS-CoV-2 re-infection, including the levels and role of anti-SARS-CoV-2 Spike protein IgG antibodies and the half-maximal concentration (IC50) of neutralizing antibodies remain unknown.Both the epidemiological and ...
Makoto Inada, Masahiro Ishikane, Mari Terada, Akihiro Matsunaga, Kenji Maeda, Kiyoto Tsuchiya, Kenji Miura, Yu Sairenji, Noriko Kinoshita, Mugen Ujiie, Satoshi Kutsuna, Yukihito Ishizaka, Hiroaki Mitsuya, Norio Ohmagari   +13 more
openaire   +2 more sources

Total Raltegravir Concentrations in Cerebrospinal Fluid Exceed the 50-Percent Inhibitory Concentration for Wild-Type HIV-1 [PDF]

Antimicrobial Agents and Chemotherapy, 2010
ABSTRACT HIV-associated neurocognitive disorders continue to be common. Antiretrovirals that achieve higher concentrations in cerebrospinal fluid (CSF) are associated with better control of HIV and improved cognition. The objective of this study was to measure total raltegravir (RAL) concentrations in CSF and to compare them with
David, Croteau, Scott, Letendre, Brookie M, Best, Ronald J, Ellis, Sheila, Breidinger, David, Clifford, Ann, Collier, Benjamin, Gelman, Christina, Marra, Gilbert, Mbeo, Allen, McCutchan, Susan, Morgello, David, Simpson, Lauren, Way, Florin, Vaida, Susan, Ueland, Edmund, Capparelli, Igor, Grant   +17 more
openaire   +3 more sources

Estimation of Serum-Free 50-Percent Inhibitory Concentrations for Human Immunodeficiency Virus Protease Inhibitors Lopinavir and Ritonavir [PDF]

Antimicrobial Agents and Chemotherapy, 2004
ABSTRACTUsing measured free fraction and 50% inhibitory concentration (IC50) values for the human immunodeficiency virus protease inhibitors lopinavir (LPV) and ritonavir (RTV) in tissue culture media with various protein concentrations ranging from 5 to 50%, we estimated serum-free IC50values for each drug.
Dean, Hickman, Sudthida, Vasavanonda, George, Nequist, Lynn, Colletti, Warren M, Kati, Richard, Bertz, Ann, Hsu, Dale J, Kempf   +7 more
openaire   +2 more sources

Determination of Diarrhetic Shellfish Poison by Measuring 50% Acid Phosphatase Activity Inhibitory Concentration (APIC₅₀)

Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 1985
A practical determination of diarrhetic shellfish poison (DSP) was established by measuring the 50% acid phosphatase activity inhibitory concentration (APIC50) with Tetrahymena pyriformis, in place of the mouse lethal assay. That is, DSP was extracted with acetone and ether from the toxic hepatopancreas of scallops, and applied to a silicic acid column.
SHIRAKI, Koichi, NAKAYA, Ken-ichi, SUGITANI, Akira, YAMADA, Fujizo   +3 more
openaire   +3 more sources

Lower than expected maraviroc concentrations in cerebrospinal fluid exceed the wild-type CC chemokine receptor 5-tropic HIV-1 50% inhibitory concentration [PDF]

AIDS, 2012
To measure maraviroc total cerebrospinal fluid (CSF) concentrations and compare them with total and unbound plasma concentrations. Total maraviroc was measured by reverse-phase high-performance liquid chromatography with tandem mass spectrometry, whereas ultrafiltration was used for unbound maraviroc. Maraviroc was detected in all nine CSF/plasma pairs
David, Croteau, Brookie M, Best, Scott, Letendre, Steven S, Rossi, Ronald J, Ellis, David B, Clifford, Ann C, Collier, Benjamin B, Gelman, Justin C, McArthur, John Allen, McCutchan, Susan, Morgello, Igor, Grant   +11 more
openaire   +2 more sources

In Vitro Effect of Copper (I) Complex [Cu(NN₁)₂](ClO₄) on Vibrio harveyi BB170 Biofilm Formation

Microorganisms, 2021
Biofilm formation in pathogenic bacteria is an important factor of resistance to antimicrobial treatments, allowing them to survive for a long time in their hosts. In the search for new antibiofilm agents, in this work we report the activity of a copper (
Sarita Soto-Aguilera, Brenda Modak, Maialen Aldabaldetrecu, Carla P. Lozano, Juan Guerrero, Claudia Lefimil, Mick Parra   +6 more
doaj   +1 more source

AVP‐IC ₅₀ Pred: Multiple machine learning techniques‐based prediction of peptide antiviral activity in terms of half maximal inhibitory concentration (IC ₅₀ ) [PDF]

Peptide Science, 2015
ABSTRACT Peptide‐based antiviral therapeutics has gradually paved their way into mainstream drug discovery research. Experimental determination of peptides' antiviral activity as expressed by their IC 50 values involves a lot of effort. Therefore, we have developed “AVP‐IC
Abid, Qureshi, Himani, Tandon, Manoj, Kumar   +2 more
openaire   +2 more sources

Antimicrobial activity of olive mill wastewater extract against Pseudomonas fluorescens isolated from mozzarella cheese

Italian Journal of Food Safety, 2016
Olive mill wastewater polyphenol extract was tested for antimicrobial activity against 64 strains of Pseudomonas fluorescens responsible for mozzarella discolouration.
Rossana Roila, Raffaella Branciari, David Ranucci, Roberta Ortenzi, Stefania Urbani, Maurizio Servili, Andrea Valiani   +6 more
doaj   +1 more source

Psoromic Acid, a Lichen-Derived Molecule, Inhibits the Replication of HSV-1 and HSV-2, and Inactivates HSV-1 DNA Polymerase: Shedding Light on Antiherpetic Properties

Molecules, 2019
Psoromic acid (PA), a bioactive lichen-derived compound, was investigated for its inhibitory properties against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), along with the inhibitory effect on HSV-1 DNA polymerase, which is a key enzyme that ...
Sherif T. S. Hassan, Miroslava Šudomová, Kateřina Berchová-Bímová, Karel Šmejkal, Javier Echeverría   +4 more
doaj   +1 more source