Results 11 to 20 of about 1,997,109 (329)

Asymptomatic COVID-19 re-infection in a Japanese male by elevated half-maximal inhibitory concentration (IC50) of neutralizing antibodies [PDF]

Journal of Infection and Chemotherapy, 2021
"Re-infection" with COVID-19 is a growing concern; re-infection cases have reported worldwide. However, the clinical characteristics of SARS-CoV-2 re-infection, including the levels and role of anti-SARS-CoV-2 Spike protein IgG antibodies and the half-maximal concentration (IC50) of neutralizing antibodies remain unknown.Both the epidemiological and ...
Makoto Inada, Masahiro Ishikane, Mari Terada, Akihiro Matsunaga, Kenji Maeda, Kiyoto Tsuchiya, Kenji Miura, Yu Sairenji, Noriko Kinoshita, Mugen Ujiie, Satoshi Kutsuna, Yukihito Ishizaka, Hiroaki Mitsuya, Norio Ohmagari   +13 more
openaire   +2 more sources

Aktivitas Antibakteri Ekstrak Etanol Daun Harendong Bulu (Clidemia Hirta) asal Maluku terhadap Staphylococcus Aureus

JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan), 2022
Pleroma urvilleanum (Clidemia hirta) is a plant that is widely found in Maluku, which contains chemical compounds, including tannins (catechols and pyrogalotanins), dioxyanthraquinones, steroids, saponins, glycosides and phenols which of these contents ...
Aulia Debby Pelu, Jayanti Djarami
doaj   +1 more source

Evaluation of Antibacterial Properties and Cytotoxicity of Ethanolic Extract of Alhagi Maurorum [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2023
Background and Objective: Cervical cancer is the fourth most common cancer in the world. The most important issue in cancer treatment is the destruction of cancer cells in the presence of normal cells.
FS Motafeghi, M Shokrzadeh, H Mohammadi, Sh Shokrzadeh, H Razaghi   +4 more
doaj  

Lower than expected maraviroc concentrations in cerebrospinal fluid exceed the wild-type CC chemokine receptor 5-tropic HIV-1 50% inhibitory concentration [PDF]

AIDS, 2012
To measure maraviroc total cerebrospinal fluid (CSF) concentrations and compare them with total and unbound plasma concentrations. Total maraviroc was measured by reverse-phase high-performance liquid chromatography with tandem mass spectrometry, whereas ultrafiltration was used for unbound maraviroc. Maraviroc was detected in all nine CSF/plasma pairs
David, Croteau, Brookie M, Best, Scott, Letendre, Steven S, Rossi, Ronald J, Ellis, David B, Clifford, Ann C, Collier, Benjamin B, Gelman, Justin C, McArthur, John Allen, McCutchan, Susan, Morgello, Igor, Grant   +11 more
openaire   +2 more sources

Inhibitory Potential of Synthetic Amino Acid Derivatives against Digestive Enzymes as Promising Hypoglycemic and Anti-Obesity Agents

Biomolecules, 2023
Over the last decades, the increased incidence of metabolic disorders, such as type two diabetes and obesity, has motivated researchers to investigate new enzyme inhibitors. In this study, the inhibitory effects of synthetic amino acid derivatives (PPC80,
Franciane Campos da Silva, Bruna Celeida Silva Santos, Pedro Pôssa de Castro, Giovanni Wilson Amarante, Orlando Vieira de Sousa   +4 more
doaj   +1 more source

Experimental therapeutic assays of Tephrosia vogelii against Leishmania major infection in murine model: in vitro and in vivo

BMC Research Notes, 2017
Background Conventional targeted leishmanicidal chemotherapy has persistently remained prohibitive for most economically deprived communities due to costs, associated time to accessing health services and duration for successful treatment programme ...
Sylvia Naliaka Marango, Christopher Khayeka-Wandabwa, Judith Alice Makwali, Bernard Ngoitsi Jumba, Joseph K. Choge, Eric Onyango Adino, Christopher O. Anjili   +6 more
doaj   +1 more source

AVP‐IC₅₀Pred: Multiple machine learning techniques‐based prediction of peptide antiviral activity in terms of half maximal inhibitory concentration (IC₅₀) [PDF]

Peptide Science, 2015
ABSTRACTPeptide‐based antiviral therapeutics has gradually paved their way into mainstream drug discovery research. Experimental determination of peptides' antiviral activity as expressed by their IC50 values involves a lot of effort. Therefore, we have developed “AVP‐IC50Pred,” a regression‐based algorithm to predict the antiviral activity in terms of
Abid, Qureshi, Himani, Tandon, Manoj, Kumar   +2 more
openaire   +2 more sources

Pharmacodynamic modelling of in vitro activity of tetracycline against a representative, naturally occurring population of porcine Escherichia coli [PDF]

, 2015
Background The complex relationship between drug concentrations and bacterial growth rates require not only the minimum inhibitory concentration but also other parameters to capture the dynamic nature of the relationship.
Agersø, Yvonne, Ahmad, Amais, Christiansen, Lasse Engbo, Damborg, Peter, Græsbøll, Kaare, Matthews, Louise, Nielsen, Søren Saxmose, Olsen, John Elmerdahl, Toft, Nils, Zachariasen, Camilla   +9 more
core   +4 more sources

Investigation on the in vitro antioxidant capacity of methanol extract, fractions and flavones from Oroxylum indicum Linn bark

Brazilian Journal of Pharmaceutical Sciences, 2018
Antioxidants from natural sources hold high values regarding their indispensible roles in the development of nutraceuticals, pharmaceuticals and cosmetic products. Oroxylum indicum L.
Do Hoang Thu Trang, Hoang Le Son, Phung Van Trung   +2 more
doaj   +1 more source

In Vitro α-Amylase, α-Glucosidase, Pancreatic Lipase, Xanthine Oxidase Inhibiting Activity of Agaricus bisporus Extracts

Mycobiology, 2023
In this study, the α-amylase inhibitory activity, α-glucosidase inhibitory activity, pancreatic lipase inhibitory activity, and Xanthine Oxidase inhibitory activity of the fruiting body extracts of 5 varieties of Agaricus bisporus (AB) were confirmed ...
Jung Han Kim, Myoung Jun Jang, Youn Jin Park   +2 more
doaj   +1 more source