The Presence of Leukocytes in Ex Vivo Assays Significantly Increases the 50-Percent Inhibitory Concentrations of Artesunate and Chloroquine against Plasmodium vivax and Plasmodium falciparum [PDF]
Antimicrobial Agents and Chemotherapy, 2011 ABSTRACT Plasmodium species ex vivo sensitivity assay protocols differ in the requirement for leukocyte removal before culturing. This study shows that the presence of leukocytes significantly increases the 50% inhibitory concentration (IC 50 ) of P. vivax
Kaewpongsri, S +11 more
openaire +3 more sources
Transcriptional Response of Selenopolypeptide Genes and Selenocysteine Biosynthesis Machinery Genes in Escherichia coli during Selenite Reduction [PDF]
, 2014 This work was supported by a United States Department of Agriculture-Cooperative State Research, Education, and Extension Service grant (no. 2009-35318-05032), a Biotechnology Research grant (no.
Tetteh, Antonia Y. +6 more
core +2 more sources
Effect of amaranth proteins on the RAS system: In vitro, in vivo and ex vivo assays [PDF]
, 2020 The aim of this work was to analyse the hypotensive effect of amaranthprotein/peptides on spontaneously hypertensive rats (SHR). The mechanism of action of these peptides was studied in vivo and ex vivo.
Aphalo, Paula +4 more
core +2 more sources
Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder [PDF]
, 2007 Acetylcholine and ATP are excitatory cotransmitters in parasympathetic nerves. We used P2X1 receptor antagonists to further characterize the purinergic component of neurotransmission in isolated detrusor muscle of guinea pig urinary bladder.
Gallagher, Gemma +3 more
core +1 more source
Synthesis and the Biological Activity of Phosphonylated 1,2,3-Triazolenaphthalimide Conjugates
Molecules, 2016 A novel series of diethyl {4-[(5-substituted-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-methyl]-1H-1,2,3-triazol-1-yl}alkylphosphonates designed as analogues of amonafide was synthesized.
Iwona E. Głowacka +6 more
doaj +1 more source
Comparison of antifungal effect of Aloevera gel and Triphala: An in vitro study
Journal of Indian Academy of Oral Medicine and Radiology, 2017 Aim: The aim of the present study was to determine and compare the antifungal and inhibitory activities of various concentrations of Aloevera gel and Triphala against oral Candiada albicans. Materials and Methods: The fungi (C.
Supreet Jain +5 more
doaj +1 more source
Influence of gallic acid on α-amylase and α-glucosidase inhibitory properties of acarbose
Journal of Food and Drug Analysis, 2016 Acarbose is an antidiabetic drug which acts by inhibiting α-amylase and α-glucosidase activities but with deleterious side effects. Gallic acid (GA) is a phenolic acid that is widespread in plant foods.
G. Oboh +3 more
semanticscholar +1 more source
In Silico screening of nonsteroidal anti-inflammatory drugs and their combined action on Prostaglandin H Synthase-1 [PDF]
, 2010 The detailed kinetic model of Prostaglandin H Synthase-1 (PGHS-1) was applied to in silico screening of dose-dependencies for the different types of nonsteroidal anti-inflammatory drugs (NSAIDs), such as: reversible/irreversible, nonselective/selective ...
Demin, Oleg +5 more
core +5 more sources
Studies on the cornin extracted from bovine liver. II. Inhibitory effect of the cornin on DNA synthesis and cell growth of L cells cultured in suspension [PDF]
, 1974 Gornin was extracted from bovine liver. The effects of cornin on DNA synthesis were compared with its effects on cell growth using L cells growing in suspension.
Ohtsuki, Hisashi
core +1 more source
Biotechnology & Biotechnological Equipment, 2019 Graptopetalum paraguayense E. Walther (GP) belongs to the Crassulaceae family and has several health benefits. In the present study we evaluated the cytotoxic, anti-Herpes Simplex virus (HSV) and antibacterial activities of a total methanol/water GP ...
Maya Margaritova Zaharieva +7 more
doaj +1 more source