Molecules, 2019 Psoromic acid (PA), a bioactive lichen-derived compound, was investigated for its inhibitory properties against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), along with the inhibitory effect on HSV-1 DNA polymerase, which is a key enzyme that ...
Sherif T. S. Hassan +4 more
doaj +1 more source
The Presence of Leukocytes in Ex Vivo Assays Significantly Increases the 50-Percent Inhibitory Concentrations of Artesunate and Chloroquine against Plasmodium vivax and Plasmodium falciparum [PDF]
Antimicrobial Agents and Chemotherapy, 2011 ABSTRACT Plasmodium species ex vivo sensitivity assay protocols differ in the requirement for leukocyte removal before culturing. This study shows that the presence of leukocytes significantly increases the 50% inhibitory concentration (IC 50 ) of P. vivax
Kaewpongsri, S +11 more
openaire +3 more sources
Assessment of the Drug Susceptibility of Plasmodium falciparum Clinical Isolates from Africa by Using a Plasmodium Lactate Dehydrogenase Immunodetection Assay and an Inhibitory Maximum Effect Model for Precise Measurement of the 50-Percent Inhibitory Concentration [PDF]
Antimicrobial Agents and Chemotherapy, 2006 ABSTRACT The extension of drug resistance among malaria-causing Plasmodium falciparum parasites in Africa necessitates implementation of new combined therapeutic strategies. Drug susceptibility phenotyping requires precise measurements.
Halima Kaddouri +4 more
openaire +1 more source
Inhibitory postsynaptic actions of taurine, GABA and other amino acids on motoneurons of the isolated frog spinal cord [PDF]
, 1975 The actions of glycine, GABA, α-alanine, β-alanine and taurine were studied by intracellular recordings from lumbar motoneurons of the isolated spinal cord of the frog.
Krumnikl, J. +9 more
core +1 more source
Synthesis and the Biological Activity of Phosphonylated 1,2,3-Triazolenaphthalimide Conjugates
Molecules, 2016 A novel series of diethyl {4-[(5-substituted-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-methyl]-1H-1,2,3-triazol-1-yl}alkylphosphonates designed as analogues of amonafide was synthesized.
Iwona E. Głowacka +6 more
doaj +1 more source
Comparison of antifungal effect of Aloevera gel and Triphala: An in vitro study
Journal of Indian Academy of Oral Medicine and Radiology, 2017 Aim: The aim of the present study was to determine and compare the antifungal and inhibitory activities of various concentrations of Aloevera gel and Triphala against oral Candiada albicans. Materials and Methods: The fungi (C.
Supreet Jain +5 more
doaj +1 more source
Biotechnology & Biotechnological Equipment, 2019 Graptopetalum paraguayense E. Walther (GP) belongs to the Crassulaceae family and has several health benefits. In the present study we evaluated the cytotoxic, anti-Herpes Simplex virus (HSV) and antibacterial activities of a total methanol/water GP ...
Maya Margaritova Zaharieva +7 more
doaj +1 more source
Oncotarget, 2016 Inconsistencies in the half-maximal (50%) inhibitory concentration (IC50) data for anticancer chemotherapeutic agents have yielded irreproducible experimental results and thus reciprocally contradictory theories in modern cancer research. The MTT assay is currently the most extensively used method for IC50 measurements.
He, Yifeng +7 more
openaire +3 more sources
The 50% inhibitory concentration (IC50) of oseltamivir against influenza B virus isolates.
, 2016 The 50% inhibitory concentration (IC50) of oseltamivir against influenza B virus isolates.
Bualan Kaewnapan (3157677) +8 more
core +1 more source
The half maximal inhibitory concentration (IC50) in each group of breast cancer cells.
, 2013 The half maximal inhibitory concentration (IC50) in each group of breast cancer cells.
Pimpicha Patmasiriwat (285301) +4 more
core +1 more source