Structure-activity relationships of fluorene compounds inhibiting HCV variants [PDF]
, 2020 Approximately 71 million people suffer from hepatitis C virus (HCV) infection worldwide. Persistent HCV infection causes liver diseases such as chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma, resulting in approximately 400,000 deaths ...
Gadhe, Changdev G. +10 more
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ING116070: a study of the pharmacokinetics and antiviral activity of dolutegravir in cerebrospinal fluid in HIV-1-infected, antiretroviral therapy-naive subjects. [PDF]
, 2014 BackgroundDolutegravir (DTG), a once-daily, human immunodeficiency virus type 1 (HIV-1) integrase inhibitor, was evaluated for distribution and antiviral activity in cerebrospinal fluid (CSF).MethodsING116070 is an ongoing, single-arm, open-label ...
Chen, Shuguang +8 more
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Characterization and Investigation of the Toxicity, Genotoxicity, Antioxidant, and Radical Scavenging Activity of Highly Fluorescent Nitrogen-Doped Graphene Quantum Dots (NGQDs) [PDF]
Iranian Journal of Chemistry & Chemical EngineeringNitrogen-Doped Graphene Quantum Dots (NGQDs) have recently been used effectively in drug delivery. Our study aimed to characterize NGQDs and investigate their toxicity and genotoxicity using the Brine Shrimp lethality test (BSLT), Allium cepa L assay ...
Mehdi Ghavamizadeh +4 more
doaj +1 more source
Biological activities and chemical composition of methanolic extracts of selected Autochthonous microalgae strains from the Red Sea [PDF]
, 2015 Four lipid-rich microalgal species from the Red Sea belonging to three different genera (Nannochloris, Picochlorum and Desmochloris), previously isolated as novel biodiesel feedstocks, were bioprospected for high-value, bioactive molecules.
Carolina Bruno De Sousa +14 more
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In Vitro Effect of Copper (I) Complex [Cu(NN1)2](ClO4) on Vibrio harveyi BB170 Biofilm Formation
Microorganisms, 2021 Biofilm formation in pathogenic bacteria is an important factor of resistance to antimicrobial treatments, allowing them to survive for a long time in their hosts. In the search for new antibiofilm agents, in this work we report the activity of a copper (
Sarita Soto-Aguilera +6 more
doaj +1 more source
Hemi-Synthesis and Anti-Oomycete Activity of Analogues of Isocordoin [PDF]
, 2017 Indexación: Web of Science; Scopus.An efficient synthesis of a series of 4-oxyalkyl-isocordoin analogues (2–8) is reported for the first time. Their structures were confirmed by1H-NMR,13C-NMR, and HRMS.
Escobar, B. +6 more
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Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 1985 A practical determination of diarrhetic shellfish poison (DSP) was established by measuring the 50% acid phosphatase activity inhibitory concentration (APIC50) with Tetrahymena pyriformis, in place of the mouse lethal assay. That is, DSP was extracted with acetone and ether from the toxic hepatopancreas of scallops, and applied to a silicic acid column.
Koichi SHIRAKI +3 more
openaire +2 more sources
Italian Journal of Food Safety, 2016 Olive mill wastewater polyphenol extract was tested for antimicrobial activity against 64 strains of Pseudomonas fluorescens responsible for mozzarella discolouration.
Rossana Roila +6 more
doaj +1 more source
Gain control network conditions in early sensory coding [PDF]
, 2013 Gain control is essential for the proper function of any sensory system. However, the precise mechanisms for achieving effective gain control in the brain are unknown.
A Couto +67 more
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Molecules, 2019 Psoromic acid (PA), a bioactive lichen-derived compound, was investigated for its inhibitory properties against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), along with the inhibitory effect on HSV-1 DNA polymerase, which is a key enzyme that ...
Sherif T. S. Hassan +4 more
doaj +1 more source