Effects of Sub-Inhibitory Rifampicin, Minocycline, and Dalbavancin on Early Biofilm Formation and Transcriptional Responses in <i>Staphylococcus aureus</i> SA113. [PDF]
MicroorganismsBieda A +7 more
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
DSD-Guided Ultrasound-Assisted Protein Recovery From Chlamydomonas reinhardtii: Modeling, Optimization, and Enzyme Inhibitory Activity Assessment. [PDF]
J Food SciLi Q +6 more
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Ultrasound-assisted deep eutectic solvent extraction combined with gradient ethanol precipitation of polysaccharides from Paulownia fortunei flowers: Process optimization, physicochemical characterization, bioactivity evaluation. [PDF]
Ultrason SonochemGuo N, Yang L, Cao XB, Zhai XQ, Fan GQ.
europepmc +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
In-Depth Biological Activities, Chemical Profiling by LC-MS/MS of Mersin, Türkiye Bee Products (Pollen, Honey, Propolis, Royal Jelly and Bee Bread). [PDF]
Moleculesİzol E, Yılmaz MA, Gülçin İ.
europepmc +1 more source