Results 121 to 130 of about 1,686,291 (300)

'Unlicensed' natural killer cells dominate the response to cytomegalovirus infection. [PDF]

, 2010
Natural killer (NK) cells expressing inhibitory receptors that bind to self major histocompatibility complex (MHC) class I are 'licensed', or rendered functionally more responsive to stimulation, whereas 'unlicensed' NK cells lacking receptors for self ...
Lanier, Lewis L, Murphy, William J, Orr, Mark T   +2 more
core   +3 more sources

Sustained attention and inhibitory control: age and sex related difference in children and adolescents using a CPT with distracting events

Frontiers in Psychology
IntroductionThe study investigates age and sex-related differences in sustained attention and inhibitory control in a sample of children and adolescents using a continuous performance test with distractor events. In addition, the impact of distractors on
Carlotta Rivella, Paola Viterbori, Maria Carmen Usai   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Controlling cluster synchronization by adapting the topology [PDF]

, 2014
We suggest an adaptive control scheme for the control of zero-lag and cluster synchronization in delay-coupled networks. Based on the speed-gradient method, our scheme adapts the topology of a network such that the target state is realized.
A. L. Fradkov, A. Rapoport, Alexander Fradkov, Anton Selivanov, D. Hebb, E. Mosekilde, Eckehard Schöll, Judith Lehnert, M. Golubitsky, P. Erdős, P. Erdős, Philipp Hövel, Y. Kuramoto   +12 more
core   +2 more sources

Differences in Executive Functioning Performance and Cortical Activation Between Autistic and Non-Autistic Youth During an fNIRS Flanker Task: A Pilot Study

Brain Sciences
Background/Objectives: Autism spectrum disorder is associated with executive functioning (EF) challenges, yet the neural correlates of EF challenges in autistic youth remain unclear.
Jung-Mei Tsai, Jacob Corey, Daisuke Tsuzuki, Anjana Bhat   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Pleasantness and Motivational Intensity of Experienced Emotion Influence Affect Labeling in Men and Women: Does Inhibitory Control Play a Role?

Psychology of Language and Communication
Affect labeling involves describing emotional experiences using words. It is not known how different aspects of emotional experience influence affect labeling. The primary objective of this study was to compare the number of affective labels generated in
Mokhtari Setareh, Jahani Amin, Hakkakan Asiyeh A’lam   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source