Results 41 to 50 of about 1,232,153 (317)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

INHIBITORY EFFECT OF BIOCIDES ON ENVIRONMENTAL S. AUREUS STRAINS

open access: yesItalian Journal of Food Safety, 2012
The aim of this study was to evaluate the inhibitory effect of biocides on S.aureus strains isolated in dairy environment. After a contact time of 5' all tested molecules showed total growth inhibition of bacteria; for lower contact time results were ...
S. Monfardini   +5 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Inhibitory Effects of Cycloheterophyllin on Melanin Synthesis [PDF]

open access: yesMolecules, 2021
This study was performed to clarify the inhibitory effects of cycloheterophyllin on melanin synthesis. In order to elucidate the inhibitory effects of cycloheterophyllin on the B16F10 cell line, cell viability, messenger ribonucleic acid (mRNA) expressions, tyrosinase activity assay, and melanin production assay were measured.
openaire   +3 more sources

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Antidiabetic activity of ajwain oil in different in vitro models

open access: yesJournal of Pharmacy and Bioallied Sciences, 2019
Context: Ajwain oil is an essential oil with thymol as its major constituent which is known for many pharmacological activities.Aims: To evaluate the anti-hyperglycaemic potential of ajwain oil using different in vitro models.Methods and Material: In ...
Nilamaideen Noorul Aneesa   +2 more
doaj   +1 more source

EVALUATION OF ANTIBACTERIAL PROPERTIES OF THREE PANAMANIAN PLANTS AGAINST MULTI-DRUG RESISTANT BACTERIA

open access: yesTecnociencia, 2020
The increased resistance of pathogenic bacteria to traditional therapy has forced the implementation of different therapies. The consequent use of more than one antibacterial drug can increase toxicity problems, an undesirable situation, especially when ...
Ramy Jhasser Martínez   +2 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Inhibitory effect of honey-sweetened goat and cow milk fermented with Bifidobacterium lactis Bb-12 on the growth of Listeria monocytogenes

open access: yesMljekarstvo, 2009
The aim of the study was to determine the influence of honey addition on fermentation of goat and cow milk with Bifidobacterium lactis Bb-12. Additionally, inhibitory potential of honey-sweetened fermented goat and cow milk against Listeria monocytogenes
Mirela Lučan   +6 more
doaj  

Uji Daya Hambat Perasan Air Kunyit (Curcuma domestica Val.) sebagai Antibakteri terhadap Pertumbuhan Bakteri Escherichia coli

open access: yesJurnal Kesehatan, 2022
Diarrhea cases in Indonesia were 270/1000 population or 7,265,013 cases occurred at all ages with a mortality rate (CFR) of 4.76% in 2018. Treatment of diarrhea can be done by giving antibiotics such as Cefotaxime, Ciprofloxacin, Gentamicin, Ampicillin ...
Nur Lulu Fitriyani   +4 more
doaj   +1 more source

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