Results 51 to 60 of about 1,832,210 (358)

Inhibitory Effects of Citrinin on Mitochondrial Function [PDF]

Agricultural and Biological Chemistry, 1987
In our preceding paper,'> we reported that citrinin, a toxic metabolite produced by several species of Penicillium and Aspergillus, has strong antifungal activity at acidic pH. This activity appears to be closely related to the respiratory inhibition observed in cell suspensions of Saccharomyces cerevisiae incubated with citrinin at acidic pH.
Hiroyuki HARAGUCHI, Toshio TANAKA, Makoto TANIGUCHI, Susumu OI, Kensuke HASHIMOTO   +4 more
openaire   +2 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Decision time, slow inhibition, and theta rhythm [PDF]

, 2010
In this paper, we examine decision making in a spiking neuronal network and show that longer time constants for the inhibitory neurons can decrease the reaction times and produce theta rhythm.We analyze the mechanism and find that the spontaneous firing
Feng, Jianfeng, Rolls, Edmund T., Smerieri, Anteo   +2 more
core   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Antidiabetic activity of ajwain oil in different in vitro models

Journal of Pharmacy and Bioallied Sciences, 2019
Context: Ajwain oil is an essential oil with thymol as its major constituent which is known for many pharmacological activities.Aims: To evaluate the anti-hyperglycaemic potential of ajwain oil using different in vitro models.Methods and Material: In ...
Nilamaideen Noorul Aneesa, Roy Anitha, Sheeja Varghese   +2 more
doaj   +1 more source

EVALUATION OF ANTIBACTERIAL PROPERTIES OF THREE PANAMANIAN PLANTS AGAINST MULTI-DRUG RESISTANT BACTERIA

Tecnociencia, 2020
The increased resistance of pathogenic bacteria to traditional therapy has forced the implementation of different therapies. The consequent use of more than one antibacterial drug can increase toxicity problems, an undesirable situation, especially when ...
Ramy Jhasser Martínez, Lilia Chérigo, Nivia Ríos   +2 more
doaj   +1 more source

Inhibitory effect of honey-sweetened goat and cow milk fermented with Bifidobacterium lactis Bb-12 on the growth of Listeria monocytogenes

Mljekarstvo, 2009
The aim of the study was to determine the influence of honey addition on fermentation of goat and cow milk with Bifidobacterium lactis Bb-12. Additionally, inhibitory potential of honey-sweetened fermented goat and cow milk against Listeria monocytogenes
Mirela Lučan, Vedran Slačanac, Jovica Hardi, Krešimir Mastanjević, Jurislav Babić, Vinko Krstanović, Marko Jukić   +6 more
doaj  

Uji Daya Hambat Perasan Air Kunyit (Curcuma domestica Val.) sebagai Antibakteri terhadap Pertumbuhan Bakteri Escherichia coli

Jurnal Kesehatan, 2022
Diarrhea cases in Indonesia were 270/1000 population or 7,265,013 cases occurred at all ages with a mortality rate (CFR) of 4.76% in 2018. Treatment of diarrhea can be done by giving antibiotics such as Cefotaxime, Ciprofloxacin, Gentamicin, Ampicillin ...
Nur Lulu Fitriyani, Rezeki Widayati, Aris Santjaka, Ristiawati Ristiawati, Jaya Maulana   +4 more
doaj   +1 more source

Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats [PDF]

, 2017
Rationale Corticostriatal circuits are widely implicated in the top-down control of attention including inhibitory control and behavioural flexibility. However, recent neurophysiological evidence also suggests a role for thalamic inputs to striatum in
A Bari, A Castañé, BN Armbruster, D Dautan, EA Schilman, ER Murphy, ES Robinson, G Paxinos, GM Alexander, HD Brown, J Groenewegen, J Wess, JN Rouder, JW Dalley, K Guillem, KM Turner, LA Bradfield, M Baviera, M Bentivoglio, M Carli, M Kimura, M Pezze, ME Ragozzino, N Amitai, N Matsumoto, NM Doig, P Aldrin-Kirk, RD Rogers, S Kinomura, SV Mahler, T Minamimoto, T Robbins, TJ Stachniak, TW Faust, V Boulougouris, Y Chudasama, Y Smith   +36 more
core   +2 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source