Results 201 to 210 of about 141,083 (247)

PhosSight: A Unified Deep Learning Framework Boosting and Accelerating Phosphoproteome Identification to Enable Biological Discoveries

Advanced Science, EarlyView.
PhosSight is a unified deep‐learning framework for phosphoproteome identification, featured by a phosphorylation‐aware detectability predictor. It improves identification sensitivity in DDA through deep re‐localization and rescoring, accelerates DIA searches by detectability‐guided spectral library pruning, and expands phosphoproteome coverage to ...
Ben Wang, Zhiyuan Cheng, Chengying She, Hongwei Zhao, Jiahui Zhang, Lin Lv, Zhihao Yan, Hongwen Zhu, Lizhuang Liu, Yan Fu, Xinpei Yi   +10 more
wiley   +1 more source

Protein language models accurately predict polymorphic peptide-modulated NK cell receptor-HLA class I interaction strengths. [PDF]

Sci Adv
AlShafey A, Nelson M, Hassan M, Kloczkowski A, Ray W, Khakoo SI, Das J.   +6 more
europepmc   +1 more source

Artificial Intelligence‐Based Body Composition Analysis Reveals Sex‐Specific Prognostic Markers and Their Clinical Value in Gastric Cancer: A Multicenter Study

Advanced Science, EarlyView.
This study applied AI to quantify multidimensional body composition from CT images in gastric cancer and healthy controls. Distinct sex‐specific patterns and disease‐related alterations were identified and were associated with survival. Higher muscle and fat measures were linked to improved outcomes.
Tianxiang Li, Tingting Liu, Qian Yang, Zhiqing Zhang, Xiaofang Guo, Xiang Wang, Yihan Zhang, Limin Ge, Yu Su, Wenjun Wu, Weihua Guo, Zheng Wang, Lian Yang, Yanfeng Niu   +13 more
wiley   +1 more source

Synchronous climbing fiber activity enables instructive signaling for cerebellar learning through modulation of disinhibitory circuits. [PDF]

Nat Neurosci
Park C, Yang Z, Nashef A, Gim J, Bahn S, Kim GH, Zhang K, Cathala L, Hong S, Im Y, Lee SH, Lee K, Kim MS, Arnold DB, Lee KJ, Christie JM, Kim JS.   +16 more
europepmc   +1 more source

Global error signal guides local optimization in mismatch calculation. [PDF]

Nat Commun
Meng JH, Wang XJ.
europepmc   +1 more source

Neuropeptide S modulation of learning and memory: a systematic review. [PDF]

Behav Brain Funct
Caragea VM, Jüngling K, Méndez-Couz M.
europepmc   +1 more source

On the impact of tactile processing on motor cortex: how touch shapes motor behaviour. [PDF]

Brain Struct Funct
Zafarana A, Muret D, Farnè A, Tamè L.
europepmc   +1 more source

Oxytocin attenuates fear learning via enhancing somatostatin interneuron-mediated local GABAergic inhibition in the prelimbic cortex. [PDF]

Sci Adv
Xu H, Li Y, Cui X, Zhang Y, Wu X, Zhuo SS, He M, Xiao L.   +7 more
europepmc   +1 more source

Expression levels of α5 subunit-containing GABA-A receptors in the prelimbic cortex are associated with visual perceptual learning

Bailey MCD, Preisler E, Sanchez CV, Prats LM, Stupart O, Versprille LJW, du Hoffmann JF, Kourtzi Z, Dalley JW.   +8 more
europepmc   +1 more source