Results 211 to 220 of about 148,630 (258)

Systemic relationships between ecological-dynamic approach and active reflection: psycho-neuro-motor, cognitive, and physiological interactions in rugby pedagogy. [PDF]

Front Sports Act Living
Rigon M, Scurati R, Merati G, Formenti D, Trecroci A, Invernizzi PL, Signorini G.   +6 more
europepmc   +1 more source

Physics‐Constrained Constitutive Learning of Rate‐Limiting Timescales for Efficient Hydrogen‐Based Direct Reduction for Green Steel Making

Advanced Science, EarlyView.
A conversion‐resolved constitutive framework is developed for the hydrogen‐based direct reduction of iron oxide pellets. Effective reaction and transport timescales are inferred directly from measured trajectories and mapped against operating conditions, pellet architecture, and composition. The analysis reveals how late‐stage transport control emerges
Anurag Bajpai, Barak Ratzker, Pasquale Cavaliere, Dierk Raabe   +3 more
wiley   +1 more source

Predicting individual differences of fear and cognitive learning and extinction. [PDF]

Nat Commun
Gomes CA, Bach DR, Razi A, Batsikadze G, Elsenbruch S, Engler H, Ernst TM, Fellner MC, Fraenz C, Genç E, Klass A, Labrenz F, Lissek S, Merz CJ, Metzen D, Nostadt A, Pawlik RJ, Schneider JE, Tegenthoff M, Thieme A, Wolf OT, Güntürkün O, Quick HH, Kumsta R, Timmann D, Spisak T, Axmacher N.   +26 more
europepmc   +1 more source

Combining Spatial Multi‐Omics Data to Decipher Spatial Domains and Elucidate Cell Heterogeneity Based on Self‐Supervised Graph Learning

Advanced Science, EarlyView.
A self‐supervised multi‐view graph fusion framework integrates spatial multi‐omics, excelling in domain identification and denoising. It reconstructs spatial pseudo‐expression, jointly analyzes multi‐omics data, infers RNA velocity, predicts spatial omics features from single‐cell multi‐omics, and detects spatially dark genes and transcription factors,
Yuejing Lu, Rui Qiao, Ying Li, Junhong Li, Nuoya Yue, Jing Ge, Jiao Wang, Luonan Chen, Peiluan Li   +8 more
wiley   +1 more source

Deep Learning and Microbiome Analysis Reveal the Preservation Mechanism of <i>Cinnamomum cassia</i> for Strawberry. [PDF]

Foods
Jiang S, Sun H, Zhang C, Zhang Y.
europepmc   +1 more source

Phase‐Resolved Defect Transport Mechanisms Governing Asynchronous Ordering in a Eutectic High‐Entropy Alloy

Advanced Science, EarlyView.
Phase‐resolved experiments and atomistic simulations reveal asynchronous ordering behaviors in a eutectic high‐entropy alloy during isothermal annealing. Distinct defect transport mechanisms are identified in coexisting B2 and BCC phases, showing that vacancy and interstitial mediated diffusion governs phase‐dependent thermal stability.
Huiwen Yao, Qingshuang Ma, Jie Xiong, Jing Bai, Huijun Li, Qiuzhi Gao   +5 more
wiley   +1 more source

An Explainable 2D-QSAR Machine Learning Approach for Predicting COX-2 Inhibitory Activity Using Molecular Fingerprints. [PDF]

Pharmaceuticals (Basel)
Ouassaf M, Alhatlani BY.
europepmc   +1 more source

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

Advanced Science, EarlyView.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong, Dong Sun, Hao‐Han Guo, Daehoon Lee, Zhipeng Liu, Lin Mei, Wen‐Cheng Xiong   +6 more
wiley   +1 more source

Synaptic plasticity of prefrontal long-range inhibition regulates cognitive flexibility. [PDF]

Neuron
Zhu X, Hagopian LL, Wallquist KE, Sohal VS.   +3 more
europepmc   +1 more source

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source