Results 231 to 240 of about 602,951 (277)

IQ Motif and SEC7 Domain-containing Protein 3 (IQSEC3) Interacts with Gephyrin to Promote Inhibitory Synapse Formation*

open access: yesJournal of Biological Chemistry, 2016
Gephyrin is a central scaffold protein that mediates development, function, and plasticity of mammalian inhibitory synapses by interacting with various inhibitory synaptic proteins. Here, we show that IQSLC3, a guanine nucleotide exchange factor for ARE6,
Eunjoon Kim   +2 more
exaly   +4 more sources

The glycinergic inhibitory synapse

Cellular and Molecular Life Sciences, 2001
Glycine is one of the most important inhibitory neurotransmitters in the spinal cord and the brainstem, and glycinergic synapses have a well-established role in the regulation of locomotor behavior. Research over the last 15 years has yielded new insights on glycine neurotransmission.
P Legendre
exaly   +3 more sources

Activity-dependent regulation of inhibitory synapse development by Npas4

open access: yesNature, 2008
Neuronal activity regulates the development and maturation of excitatory and inhibitory synapses in the mammalian brain. Several recent studies have identified signalling networks within neurons that control excitatory synapse development.
Tae-Kyung Kim   +2 more
exaly   +2 more sources

Hyperventilation and inhibitory synapses

Experientia, 1979
Injection of a subconvulsive dose of strychnine (which blocked the inhibitory synapses) increases respiratory muscle activity evoked by stimulation of a sciatic nerve as well as by inhalation of hypercapnic gas mixture. Thus the inhibitory synapses prevent an excessive hyperventilation.
S I, Frankshteĭn   +2 more
openaire   +3 more sources

Constructing inhibitory synapses

Nature Reviews Neuroscience, 2001
Control of nerve-cell excitability is crucial for normal brain function. Two main groups of inhibitory neurotransmitter receptors--GABA(A) and glycine receptors--fulfil a significant part of this role. To mediate fast synaptic inhibition effectively, these receptors need to be localized and affixed opposite nerve terminals that release the appropriate ...
S J, Moss, T G, Smart
openaire   +2 more sources

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