Results 91 to 100 of about 1,589,274 (291)

Investigating the stellar system's life-time and the evolution of their mass function using N-body simulation [PDF]

open access: yesarXiv, 2012
In this thesis we study several aspects of dynamical evolution of stellar clusters. The results of more than 200 simulations of single-mass star clusters with different initial total mass, half-mass radius and galactocentric distance, are reported. Recent studies of star clusters show a linear relation between a star cluster's dissolution time and its ...
arxiv  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

The Panchromatic Hubble Andromeda Treasury: Triangulum Extended Region (PHATTER). VI. The High-mass Stellar Initial Mass Function of M33

open access: yesThe Astronomical Journal
We measure the high-mass stellar initial mass function (IMF) from resolved stars in M33 young stellar clusters. Leveraging the Hubble Space Telescope’s high resolving power, we fully model the IMF probabilistically.
Tobin M. Wainer   +17 more
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Experimental research on low and strength characteristics of coal slime based cemented filling material

open access: yesMeitan kexue jishu
To study the flow and strength characteristics of coal slime based backfill materials, orthogonal tests were used to design one cemented backfill material combining coal slime, high-water-content materials, cement, and fly ash.
Baifu AN   +5 more
doaj   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

The Initial Mass Function Based on the Full-sky 20 pc Census of ∼3600 Stars and Brown Dwarfs

open access: yesThe Astrophysical Journal Supplement Series
A complete accounting of nearby objects—from the highest-mass white dwarf progenitors down to low-mass brown dwarfs—is now possible, thanks to an almost complete set of trigonometric parallax determinations from Gaia, ground-based surveys, and Spitzer ...
J. Davy Kirkpatrick   +85 more
doaj   +1 more source

К ВОПРОСУ О ВКЛАДЕ ВЫРОЖДЕННЫХ КАРЛИКОВ БЛИЖАЙШИХ ОКРЕСТНОСТЕЙ СОЛНЦА, ГАЛО И НАСЕЛЕНИЯ III В МАССУ ТЕМНОЙ МАТЕРИИ

open access: yesOdessa Astronomical Publications, 2011
The data about occurrence frequency of substars and white dwarfs among close stars are analyzed. The estimation of partial content of subdwarfs and stellar remains among populations II and III as function of power of initial mass function have been made.
В. А. Захожай   +2 more
doaj   +1 more source

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