Results 101 to 110 of about 1,052,124 (265)

SYHA1813, A VEGFR and CSF1R Inhibitor, in Patients With Recurrent High‐Grade Gliomas: A Multicenter, Open‐Label Phase I Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang, Shenglan Li, Liang Wang, Qianxue Chen, Weiguo Hu, Ting Lei, Ying Mao, Jing Zhang, Xiaojun Xiang, Qiming Wang, Zhengwen He, Tao Sun, Yulei Wang, Mengqian Huang, Rong Zhang, Feng Chen, Wenbin Li   +16 more
wiley   +1 more source

Aeos: The Impact of Population III Initial Mass Function and Star-by-star Models in Galaxy Simulations

The Astrophysical Journal
We explore the effect of variations in the Population III initial mass function (IMF) and star-by-star feedback on early galaxy formation and evolution using the A eos simulations. We compare simulations with two different Population III IMFs: M _char  = 
Kaley Brauer, Jennifer Mead, John H. Wise, Greg L. Bryan, Mordecai-Mark Mac Low, Alexander P. Ji, Andrew Emerick, Eric P. Andersson, Anna Frebel, Benoit Côté   +9 more
doaj   +1 more source

Color Gradients Within Globular Clusters: Restricted Numerical Simulation [PDF]

Journal of Astronomy and Space Sciences, 1997
The results of a restricted numerical simulation for the color gradients within globular clusters have been presented. The standard luminosity function of M3 and Salpeter's initial mass functions were used to generate model clusters as a fundamental ...
Young-Jong Sohn, Mun-Suk Chun
doaj  

THE INITIAL MASS FUNCTION AND DISK FREQUENCY OF THE ρ OPHIUCHI CLOUD: AN EXTINCTION-LIMITED SAMPLE [PDF]

, 2011
Kristen L. Erickson, Bruce A. Wilking, Michael R. Meyer, John G. Robinson, Lauren N. Stephenson   +4 more
openalex   +1 more source

Practice Recommendations for Genetic Testing of Ataxias

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan, Amy D. Mook, Michelle Rochman, Jin Yun Helen Chen, Weiyi Mu, George R. Wilmot, Liana S. Rosenthal, Wendy R. Uhlmann   +7 more
wiley   +1 more source

Suppressed Cosmic-Ray Energy Densities in Molecular Clouds from Streaming Instability-regulated Transport

The Astrophysical Journal
Cosmic rays (CRs) are the primary driver of ionization in star-forming molecular clouds (MCs). Despite their potential impacts on gas dynamics and chemistry, no simulations of star cluster formation following the creation of individual stars have ...
Margot Fitz Axen, Stella Offner, Philip F. Hopkins, Mark R. Krumholz, Michael Y. Grudić   +4 more
doaj   +1 more source

THE INITIAL MASS FUNCTION OF EARLY-TYPE GALAXIES [PDF]

, 2010
Tommaso Treu, Matthew W. Auger, L. V. E. Koopmans, R. Gavazzi, Philip J. Marshall, A. Bolton   +5 more
openalex   +1 more source

Cognitive Impairment in Multiple Sclerosis: The Role of Clinical and Sociodemographic Factors ‐ A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment (CI) affects the quality of life in multiple sclerosis (MS). Identifying influencing factors is key to improving CI monitoring. This systematic review and meta‐analysis examines clinical and sociodemographic variables impacting the cognitive screening Symbol Digit Modalities Test (SDMT) performance across MS ...
Katalin Lugosi, Marie A. Engh, Tamás Kói, Zsolt Molnár, Gábor Csukly, Klaudia Horváth, Emma Hargitai, Péter Hegyi, Zsolt Mezei   +8 more
wiley   +1 more source

Evidence of Cosmic Evolution of the Stellar Initial Mass Function [PDF]

, 2008
Pieter G van Dokkum, Pieter G van Dokkum
openalex   +1 more source

Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

Annals of Clinical and Translational Neurology, EarlyView.
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski, Freddy Chafota, Fangyuan Cao, Amanda Wei Yin Lim, Victor Flores‐Ocampo, Santiago Díaz‐Torres, Zuriel Ceja, Luis M. García‐Marín, Scott F. Farrell, Kishore R. Kumar, Jane Alty, George D. Mellick, Trung Thành Ngô, Miguel E. Rentería   +13 more
wiley   +1 more source