Results 101 to 110 of about 143,162 (326)

Prospects of dynamical determination of General Relativity parameter beta and solar quadrupole moment J2 with asteroid radar astronomy

, 2017
We evaluated the prospects of quantifying the parameterized post-Newtonian parameter beta and solar quadrupole moment J2 with observations of near-Earth asteroids with large orbital precession rates (9 to 27 arcsec century$^{-1}$). We considered existing
Greenberg, Adam H., Margot, Jean-Luc, Verma, Ashok K.   +2 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Initial Values Determination of Thrust Parameters for Continuously Low-Thrust Maneuvering Spacecraft

Applied Sciences
Continuous low thrust is widely used in orbit transfer maneuvers. If the unknown maneuvers are not correctly compensated, the orbiting accuracy will be seriously affected.
Wen Guo, Xuefeng Tao, Min Hu, Wen Xue
doaj   +1 more source

A Method to Determine BeiDou GEO/IGSO Orbital Maneuver Time Periods

Sensors, 2019
Because there are different types of BeiDou constellations with participating geostationary orbit (GEO) and inclined geosynchronous orbit (IGSO) satellites, the maneuvering frequency of BeiDou satellites is higher than that of other navigation systems ...
Zhiwei Qin, Guanwen Huang, Qin Zhang, Le Wang, Xingyuan Yan, Yanchao Kang, Xiaolei Wang, Shichao Xie   +7 more
doaj   +1 more source

An analytical initial orbit determination method using two observations from a bistatic radar

, 2022
Jinye Qu, Tuo Fu, Defeng Chen, Huawei Cao, Shuo Zhang   +4 more
openalex   +1 more source

LARES Satellite Thermal Forces and a Test of General Relativity

, 2016
We summarize a laser-ranged satellite test of frame-dragging, a prediction of General Relativity, and then concentrate on the estimate of thermal thrust, an important perturbation affecting the accuracy of the test.
Brooks, Jason, Ciufolini, Ignazio, Gurzadyan, Vahe, Khachatryan, Harutyun, Koenig, Rolf, Matzner, Richard, Mirzoyan, Sergey, Nguyen, Phuc, Paolozzi, Antonio, Paris, Claudio, Pavlis, Erricos C., Penrose, Roger, Ries, John, Sindoni, Giampiero   +13 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Initial Orbit Determination of a Space Object from Limited Angular Optical Measurements

Приборы и методы измерений
Currently, the problem of initial orbit determination for space objects based on angular coordinate measurements (right ascension and declination) under limited data conditions is of significant practical value.
V. S. Baranova, A. A. Spiridonov, D. V. Ushakov, V. A. Saetchnikov   +3 more
doaj   +1 more source