Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang +13 more
wiley +1 more source
Selective targeting of a histone-like silencer Sfx to the R6K conjugal transfer operon. [PDF]
Wang B +8 more
europepmc +1 more source
Adaptive Genomic Divergence Across Altitudes in Capsella bursa‐pastoris
Genomic divergence was observed between high‐altitude and low‐altitude populations of Capsella bursa‐pastoris in China, consistent with an important role of ecological factors. Candidate adaptive loci associated with enhanced energy metabolism, photoprotection, and growth plasticity under altitudinal stress were identified.
Lu Liu +4 more
wiley +1 more source
Complete genome sequence of <i>Rahnella</i> sp. PAMC25559, a psychrophilic plant growth-promoting bacterium isolated from an Alpine glacier. [PDF]
Bang J +5 more
europepmc +1 more source
The power of many: when genetics met yeasts and high‐throughput
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
Aneuploidy alleviates the cell proliferation defect caused by mutations affecting origin licensing in Saccharomyces cerevisiae. [PDF]
de La Roche Saint-André C.
europepmc +1 more source
The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke +2 more
wiley +1 more source
Sex-Specific Factors Influencing HIV Infection. [PDF]
Pujantell M, Altfeld M.
europepmc +1 more source
R-loops as a trigger for intra- and extrachromosomal DNA amplification in cancer. [PDF]
Kovalenko TF +4 more
europepmc +1 more source
Rare genetic diseases associated with G-quadruplex-induced replication stress. [PDF]
Herr LM +6 more
europepmc +1 more source

