Results 101 to 110 of about 91,513 (309)
Prisoners' views of injecting drug use and harm reduction in Irish prisons. [PDF]
, 2004 Drug misuse and hepatitis C are known to be endemic in Irish prisons. Using a grounded theory approach, this qualitative study sought to examine prisoners' views of drug injecting practices and harm reduction interventions in Dublin prisons.
Long, Jean, Allwright, Shane, Begley, C.
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Trends in property and illicit drug crime around the Medically Supervised Injecting Centre in Kings Cross: 2012 update [PDF]
, 2013 Aim: The Medically Supervised Injecting Centre (MSIC) opened in Kings Cross in May 2001. This paper examines whether there have been: (i) increases in the volume of robbery, theft and illicit drug offences in Kings Cross Local Area Command (LAC) up until
Nicole Mahoney, Neil Donnelly
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A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
Injecting risk behaviours, self-reported mental health and crime [PDF]
, 2013 This paper explores differences between two types of illicit drug users (heroin users and non-heroin users) in relation to injecting risk behaviours, self-reported mental health, driving and crime.Key findingsParticipants were divided into two groups ...
Jennifer Stafford, Lucy Burns
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Factors mediating HIV risk among female sex workers in Europe: a systematic review and ecological analysis. [PDF]
, 2013 OBJECTIVES: We reviewed the epidemiology of HIV and selected sexually transmitted infections (STIs) among female sex workers (FSWs) in WHO-defined Europe.
Platt, Lucy +13 more
core +1 more source
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Safer injecting: reducing the harm associated with injecting drug use. [PDF]
, 2008 This guide is aimed at people who inject drugs to help reduce some of the problems caused by injecting. It includes: • Information on safer injecting practices and types of injecting.
core
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source