Results 71 to 80 of about 2,272,899 (317)

Diesel engine fuel injection monitoring using acoustic measurements and independent component analysis [PDF]

, 2010
Air-borne acoustic based condition monitoring is a promising technique because of its intrusive nature and the rich information contained within the acoustic signals including all sources.
Gu, Fengshou, Ball, Andrew, Ball, A. D., Albarbar, A., A.D. Ball, Gu, F., A. Albarbar, F. Gu   +7 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A review of micro-powder injection moulding as a microfabrication technique [PDF]

, 2011
Micro-powder injection moulding (µPIM) is a fast-developing micro-manufacturing technique for the production of metal and ceramic components. Shape complexity, dimensional accuracy, replication fidelity, material variety combined with high- volume ...
Alcock, Jeffrey R., Usama M Attia, Jeffrey R Alcock, Attia, Usama M.   +3 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Sandwich injection moulding with thermoset materials [PDF]

This project aimed to study the feasibility of making a thermoset sandwich injection moulding from a novel thermoset co-injection moulding system. Two thermoset polyesters, BMC and a powder coating, were used for all experiments.
Kiatmanaroj, Subongkoj
core  

Investigation of split injection in a single cylinder optical diesel engine

, 2010
SAE paper 2010-01-0605, Copyright © 2010 SAE International. This paper is posted on this site with permission from SAE International, and is for viewing only.
Diez, A, Alvaro Diez, Hua Zhao, Zhao, H
core   +1 more source

Clinical Translation Challenges and Strategies for Tumour Vaccines Considering Multiple Delivery Routes

Vaccines
Background: The high incidence and mortality rates of cancer have kept it at the top of the research agenda for the global healthcare industry, as well as put serious economic pressure on families and society.
Ruiyun Song, Xiao Li, Junsong Zhu, Jian He, Jintong Na   +4 more
doaj   +1 more source

Entesopathy of the lateral epicondyle of the humeral bone – current treatment options

Journal of Education, Health and Sport, 2020
Chronic pain located on the lateral surface of the elbow in the area of the lateral epicondyle of the humerus is characteristic for a disease called tennis elbow, which belongs to the group of enthesopathies, i. e.
Kamil Fatyga, Marta Tarczyńska, Krzysztof Gawęda, Rafał Mazur, Łukasz Głodek   +4 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Near-threshold electron injection in the laser-plasma wakefield accelerator leading to femtosecond bunches [PDF]

, 2015
We gratefully acknowledge the support of the UK EPSRC (grant no. EP/J018171/1), the EU FP7 programmes: the Extreme Light Infrastructure (ELI) project, the Laserlab-Europe (no. 284464), and the EUCARD-2 project (no.
Jaroszynski, D.A., Jaroszynski, D A, Anania, M P, Brunetti, E, Anania, M.P., Welsh, G.H., Raj, G, Ersfeld, B, Cipiccia, S., Noble, A., Ersfeld, B., Raj, G., Cairns, R Alan, Islam, M R, Shanks, R P, Welsh, G H, Cairns, R.A., Issac, R C, Issac, R.C., Wiggins, S M, Islam, M.R., Noble, A, Cipiccia, S, Shanks, R.P., Brunetti, E., Wiggins, S.M., Cairns, R A   +26 more
core   +1 more source