Results 91 to 100 of about 8,725,002 (325)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Three-point Method Nerve Block for Relieving Pain of Microbotox Injection in Middle and Upper Face

Plastic and Reconstructive Surgery, Global Open
Background:. With the popularity of microbotox, pain caused by multiple microdroplets and subcutaneous injection of botulinum toxin is increasing. This study presents a new, refined, three-point nerve block technique that provides effective pain relief ...
Bing Liu, MD, Xueshang Su, MM, Hongli Chai, MM, Qi Chen, BM, Jintian Hu, MD, Yongqian Wang, MD   +5 more
doaj   +1 more source

Single-point versus double-point injection technique of ultrasound-guided supraclavicular block: A randomized controlled study

Journal of Anaesthesiology Clinical Pharmacology, 2019
Background and Aims: This study aims to compare the single-point injection and double-point injection technique of ultrasound-guided supraclavicular block with regard to the success rate, time taken to perform the procedure, onset and duration of sensory
Nitin Choudhary, Abhijit Kumar, Amit Kohli, Sonia Wadhawan, Tabish H Siddiqui, Poonam Bhadoria, Hemlata Kamat   +6 more
doaj   +1 more source

Influence of several factors on ignition lag in a compression-ignition engine [PDF]

This investigation was made to determine the influence of fuel quality, injection advance angle, injection valve-opening pressure, inlet-air pressure, compression ratio, and engine speed on the time lag of auto-ignition of a Diesel fuel oil in a single ...
Gerrish, Harold C, Voss, Fred
core   +1 more source

Ponderomotive scattering of an electron-bunch before injection into a laser wakefield [PDF]

, 2006
For the purpose of laser wakefield acceleration, it turned out that also the injection of electron bunches longer than a plasma wavelength can generate accelerated femtosecond bunches with relatively low energy spread.
Boller, K. -J., Khachatryan, A. G., Luttikhof, M. J. H., van Goor, F. A.   +3 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A New Characterization Method for Dynamic Connectivity Field Between Injection and Production Wells in Offshore Reservoir

Journal of Marine Science and Engineering
Connectivity between injection and production wells is critical for efficient oil production, especially in offshore reservoirs where the number of wells is limited.
Changchun Guo, Yuzhou Hu, Li Tao, Mengna Cheng, Fankun Meng, Hui Zhao, Fengshuang Du   +6 more
doaj   +1 more source

Investigations of Effects of Surface Temperature and Single Roughness Elements on Boundary-Layer Transition [PDF]

, 1947
The laminar boundary layer and the position of the transition point are investigated on a heated flat plate. It was found that the Reynolds number of transition decreases as the temperature of the plate is increased.
Fila, Gertrude H., Liepmann, Hans W.
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source