Results 91 to 100 of about 15,924,839 (382)

Investigation on an Injection Strategy Optimization for Diesel Engines Using a One-Dimensional Spray Model

Energies, 2019
Common rail systems have been widely used in diesel engines due to the stricter emission regulations. The advances in injector technology and ultrahigh injection pressure greatly promote the development of multiple-injection strategy, leading to the ...
Intarat Naruemon, Long Liu, Qihao Mei, Xiuzhen Ma   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Variation of cosmic ray injection across supernova shocks

, 2003
The injection rate of suprathermal protons into the diffusive shock acceleration process should vary strongly over the surface of supernova remnant shocks. These variations and the absolute value of the injection rate are investigated.
Allen, Bamba, Bell, Bell, Bennet, Berezhko, Berezhko, Berezhko, Berezhko, Berezhko, Berezhko, Blandford, Borkowski, Dieckmann, Dorfi, E. G. Berezhko, Ellison, Galeev, Galeev, Garcia-Segura, H. J. Völk, Koyama, L. T. Ksenofontov, Levinson, Lucek, Lucy, Lucy, Malkov, Malkov, Malkov, McClements, McKenzie, Ratkiewicz, Reynoso, Scholer, Trattner, Völk   +36 more
core   +1 more source

Effect of fuel injection rate shapes on mixture formation and combustion characteristic in a free-piston diesel engine generator

, 2018
The free-piston engine generator is a new power machinery, which removes the crank-shaft mechanism. This article aims to study the impact of different injection rate shapes (left triangle, rectangle, and right triangle) on the free-piston engine ...
Cuijie Han, Chenheng Yuan, Yituan He, Yang Liu   +3 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Numerical Modeling of Variable Fluid Injection-Rate Modes on Fracturing Network Evolution in Naturally Fractured Formations

Energies, 2016
In this study, variable injection-rate technology was numerically investigated in a pre-existing discrete fracture network (DFN) formation, the Tarim Basin in China.
Yu Wang, Xiao Li, Bo Zhang
doaj   +1 more source

Evaluation of the effect of intrauterine injection of platelet-rich plasma on the pregnancy rate of patients with a history of implantation failure in the in vitro fertilization cycle

, 2022
Sara Ershadi, Narjes Noori, Alireza Dashipoor, Marzieh Ghasemi, Nahid Shamsa   +4 more
openalex   +1 more source

The effectiveness of a double-stem injection valve in controlling combustion in a compression-ignition engine [PDF]

An investigation was made to determine to what extent the rates of combustion in a compression-ignition engine can be controlled by varying the rates of fuel injection.
Spanogle, J A, Whitney, E G
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Numerical Simulation of the Simultaneous Development of Multiple Fractures in Horizontal Wells Based on the Extended Finite Element Method

Energies
Simultaneous multiple-fracture treatments in horizontal wellbores have become an essential technology for the economic development of shale gas reservoirs. During hydraulic fracturing, fracture initiation and propagation always induce additional stresses
Enshun Ping, Peng Zhao, Haiyan Zhu, Yuzhong Wang, Zixi Jiao, Qingjie Zhao, Gan Feng   +6 more
doaj   +1 more source