Results 101 to 110 of about 163,246 (289)
Bio-Protocol, 2018 Eye drop treatments are typically used to apply drugs to the anterior structures of the eye. Recently, however, studies have demonstrated that eye drops can reach the retina in the back of the eye if pharmacological agents are carried in appropriate ...
Cindy Linn, Sarah Webster, Mark Webster
doaj +1 more source
Adriamycin-loaded albumin-heparin conjugate microspheres for intraperitoneal chemotherapy [PDF]
, 1994 Adriamycin-loaded albumin-heparin conjugate microspheres (ADR-AHCMS) were evaluated as possible intraperitoneal (i.p.) delivery systems for site-specific cytotoxic action.
Bae, Y.H. +9 more
core +3 more sources
Advanced Functional Materials, EarlyView.ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian +5 more
wiley +1 more source
Radiation Oncology, 2009 Background Alkylphosphocholines represent promising antineoplastic drugs that induce cell death in tumor cells by primary interaction with the cell membrane.
Wachholz Kirsten +9 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni +8 more
wiley +1 more source
Journal of University Medical & Dental College, 2019 OBJECTIVE: To determine the efficacy of intraperitoneal bupivacaine in post operative pain relief following cholecystectomy in comparison with intravenous tramadol.
Gohar latif Kalas +4 more
doaj
Advanced Functional Materials, EarlyView.This study develops a self‐powered permeable electronic dressing (SPED) that synergistically integrates exudate management, electrical stimulation, and on‐demand drug delivery. The dressing effectively absorbs exudate while demonstrating potent antibacterial activity and accelerated tissue regeneration in diabetic mouse models, thereby promoting ...
Jiaheng Liang +12 more
wiley +1 more source
Effect of PlGF-inhibition on survival in mice with hepatocellular carcinoma [PDF]
, 2010 Background: Inhibition of angiogenesis is currently hot topic in the search for an effective treatment for hepatocellular carcinoma (HCC). Up till recently, the focus was mainly on VEGF, an important regulator in the pathologic and physiologic ...
Carmeliet, Peter +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin +5 more
wiley +1 more source
Veterinary Medicine International, 2017 Published reports of status epilepticus due to intraperitoneal injection containing propylene glycol in rats are sparse. In fact, there are no reports specifying a maximum safe dose of propylene glycol through intraperitoneal administration.
Evon S. Ereifej +5 more
doaj +1 more source