Results 101 to 110 of about 300,512 (305)
Radiation Oncology, 2009 Background Alkylphosphocholines represent promising antineoplastic drugs that induce cell death in tumor cells by primary interaction with the cell membrane.
Wachholz Kirsten +9 more
doaj +1 more source
Soft and Transient Bioelectronics Enabled by Polymer‐Free Ti3C2Tx MXene Hydrogels
Advanced Materials, EarlyView.We present Ti3C2Tx MXene hydrogel (MXgel) bioelectronics, a soft, flexible, and fully transient platform for high‐fidelity neural recording and stimulation. MXgel bioelectronics exhibit exceptional electrical conductivities, low electrochemical impedances, and high charge injection capacities.
Raghav Garg +15 more
wiley +1 more source
Association of Anti-VEGF Injections with Progression of Geographic Atrophy
, 2016 Age-related macular degeneration (AMD) is one of the leading causes of blindness in developed countries in people over the age of 60 years. One of the forms of advanced AMD is wet AMD.
Sravanthi Vegunta +5 more
core +1 more source
PLoS ONE, 2019 Leptomeningeal metastasis remains a difficult clinical challenge. Some success has been achieved by direct administration of therapeutics into the cerebrospinal fluid (CSF) circumventing limitations imposed by the blood brain barrier.
Gregory M Shackleford +8 more
doaj +1 more source
Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency
Advanced Materials, EarlyView.As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang +12 more
wiley +1 more source
Double-Emulsion Copolyester Microcapsules for Sustained Intraperitoneal Release of Carboplatin [PDF]
, 2019 Despite on-going medical advances, ovarian cancer survival rates have stagnated. In order to improve IP delivery of platinum-based antineoplastics, we aimed to develop a sustained drug delivery system for carboplatin (CPt).
Marek, Droździk +7 more
core +1 more source
The effect of melatonin on coagulation parameters in rats with cerulein-induced acute pancreatitis [PDF]
Eurasian Journal of Veterinary SciencesAim: The aim of this study was to evaluate possible effects of melatonin on coagulation parameters in rats with cerulein induced acute pancreatitis. Materials and Methods: For this purpose, 32 adult, male, healthy Wistar Abino rats were used. The animals
Ercan Keskin, Deniz Uluışık
doaj
3D Printed Photon Shield Assembly for Low‐Noise Visual Stimulation During Two‐Photon Imaging in Mice
Advanced Materials Technologies, EarlyView.We present the Photon Shield, an open‐hardware system for low‐noise two‐photon calcium imaging during visual stimulation in mice. Combining a 3D‐printed headplate and rail‐mounted shield substantially reduces stray‐light contamination, as quantitatively verified. Functional validation confirms reliable cortical responses. Open design files enable broad
Gergely Katona +6 more
wiley +1 more source
Effectiveness of Ultrasound Guided Intraarticular Injections with Lidocaine and Triamcinolone: A Retrospective Study of Primary Hip Injections [PDF]
Maya Jurgens, Tarandeep Sidhu, Amir A Jamali Department of Orthopedic Surgery, Joint Preservation Institute, Walnut Creek, CA, USACorrespondence: Amir A Jamali, Department of Orthopedic Surgery, Joint Preservation Institute, 100 N. Wiget Lane, Suite 200,
Jamali AA, Jurgens M, Sidhu T
core
Advanced Science, EarlyView.IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu +8 more
wiley +1 more source