Results 121 to 130 of about 163,246 (289)

Evaluation of the Immunosafety of Cucurbit[n]uril In Vivo

Pharmaceutics
Cucurbiturils are a family of macrocyclic oligomers capable of forming host–guest complexes with various molecules. Due to noncovalent binding to drug molecules and low toxicity, cucurbiturils has been extensively investigated as potential carriers for ...
Ekaterina Pashkina, Alina Aktanova, Olga Boeva, Maria Bykova, Elena Gavrilova, Elena Goiman, Ekaterina Kovalenko, Na’il Saleh, Lyubov Grishina, Vladimir Kozlov   +9 more
doaj   +1 more source

Metabolism of Intraperitoneally Injected Serum Protein.

Experimental Biology and Medicine, 1939
Two groups of 10 albino rats with identical average body weights were selected. For 2 days they were given no food. On the morning and evening of each day 12 cc of 6.4% dextrose in 0.9% sodium chloride was injected into the peritoneal cavities of the controls while to the experimental group an injection of 12 cc of freshly separated serum obtained from
openaire   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Differential neutrophil responses in murine following intraperitoneal injections of Escherichia coli and Staphylococcus aureus

Heliyon
Objective: This study aimed to investigate the proportion of neutrophils among leukocytes, in various tissues following intraperitoneal injection of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in mice.
Yanyan Zhu, Jingya Luo, Xianzhu Xia, Hao Feng, Pingsen Zhao   +4 more
doaj   +1 more source

Apolipoprotein E delivery by peritoneal implantation of encapsulated recombinant cells improves the hyperlipidaemic profile in apoE-deficient mice [PDF]

, 2005
Plasma apolipoprotein E (apoE) is a 34-kDa polymorphic protein which has atheroprotective actions by clearing remnant lipoproteins and sequestering excess cellular cholesterol.
Diakonov, IA, Dickson, G, Graham, IR, Harris, JD, Heald, KA, Mulcahy, JV, Owen, JS, Tagalakis, AD   +7 more
core  

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Fructose improves titanium dioxide nanoparticles induced alterations in developmental competence of mouse oocytes

BMC Veterinary Research
Aims We investigated the effects of intraperitoneal injections of titanium dioxide nanoparticles (TiO2 NPs, 100 mg/kg) for 5 consecutive days on the developmental competence of murine oocytes. Furthermore, study the effects of TiO2 NPs on antioxidant and
Mohammed A Elmetwally, Amal Helmy, Ahmed Balboula, Mohamed Eladl, Basma Hamed, Samah Lashen, Shaymaa Rezk, Amira Yaseen, Heba Sharawy, Mamdouh Hussien, Samy Zabel, Abdelmonem Montaser, Amal Halawa   +12 more
doaj   +1 more source

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

Advanced Healthcare Materials, EarlyView.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han, Donghyun Kim, Haram Lee, Dong‐Wook Park, Sung Soo Kwak, Joohee Kim   +5 more
wiley   +1 more source

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

Acute hematologic, hepatologic, and nephrologic changes after intraperitoneal injections of 18 nm gold nanoparticles in hamsters

International Journal of Nanomedicine, 2016
Hazem Mohamed Saleh,1 Omar A Soliman,2 Mohamed Osama Elshazly,3 Alaa Raafat,2 Adel K Gohar,2 Taher A Salaheldin41Otolaryngology Unit, Department of Medical Applications, The National Institute of Laser Enhanced Sciences, Cairo University, 2Department of ...
Saleh HM, Soliman OA, Elshazly MO, Raafat A, Gohar AK, Salaheldin TA   +5 more
doaj