Results 211 to 220 of about 153,401 (288)

A BALB/c mouse model of Mycobacterium abscessus lung infection based on once-weekly cyclophosphamide administration.

Dis Model Mech
Rimal B, Panthi CM, Howe RA, Lamichhane G.   +3 more
europepmc   +1 more source

A blocking antibody against anti-Müllerian hormone restores ovulation and normal androgen levels in a spontaneous rat model of polycystic ovary syndrome. [PDF]

EBioMedicine
Racine C, Fraissinet F, Tolu S, Pereira T, Gil S, Badel A, Bailbé D, Fève B, Movassat J, Cate R, di Clemente N.   +10 more
europepmc   +1 more source

Pharmacological modulation of tumor interstitial fluid pressure (IFP) to enhance intraperitoneal chemotherapy (IPC) [PDF]

, 2014
Ceelen, Wim, Descamps, Benedicte, Gremonprez, Félix, Izmer, Andrei, Pattyn, Piet, Vanhaecke, Frank, Vanhove, Christian   +6 more
core   +1 more source

PRMT5 Inhibitor Synergizes with Chemotherapy to Induce Resembling Mismatch Repair Deficiency and Enhance Anti‐TIGIT Therapy in Microsatellite‐Stable Colorectal Cancer

Advanced Science, EarlyView.
Microsatellite‐stable (MSS) colorectal cancer (CRC) resists immunotherapy. PRMT5 inhibition enhances CPT‐11 sensitivity, inducing a PMS2‐deficient‐like state and cytosolic dsDNA release, which activates the cGAS‐STING pathway to promote anti‐tumor immunity. However, this combination therapy upregulates TIGIT expression on CD8+ T cells, and the addition
Jiang Zhu, Shenao Fu, Xi Zou, Hanjiang Zeng, Guangzu Cui, Yinghui Peng, Diya Tang, Fan Zhang, Hong Shen, Shan Zeng, Ying Han   +10 more
wiley   +1 more source

Human umbilical cord mesenchymal stem cells toxicity and allergy effects: In vivo assessment. [PDF]

PLoS One
Cheng WD, Bin L, Lin ZX, Yu D, Xiang DK, Lo S, Ravichandran M, Kong TS.   +7 more
europepmc   +1 more source

Fate of kidney metallothionein intraperitoneally injected into the rat.

Chemical and Pharmaceutical Bulletin, 1979
Shinji Takenaka, Kazuo T. Suzuki
openaire   +4 more sources

MYC/TET3‐Regulated TMEM65 Activates OXPHOS‐SERPINB3 Pathway to Promote Progression and Cisplatin Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) remains a major challenge in breast cancer management as it lacks effective therapeutic targets. This study uncovers that MYC/TET3‐regulated mitochondrial inner‐membrane protein TMEM65 promotes TNBC progression and cisplatin resistance by activating the OXPHOS‐SERPINB3 pathway and reveals TMEM65 as a potential ...
Yin‐Ling Zhang, Min‐Ying Huang, Shao‐Ying Yang, Jia‐Yang Cai, Qian Zhao, Fang‐Lin Zhang, Xin Hu, Zhi‐Min Shao, Li Liao, A‐Yong Cao, Da‐Qiang Li   +10 more
wiley   +1 more source

Peptide Family Promotes Brain Cell Rejuvenation and Improved Cognition through Peripheral Delivery. [PDF]

ACS Omega
Anton-Fernandez A, Domene-Serrano I, Cuadros R, Peinado-Cahuchola R, Sanchez-Pece M, Hernandez F, Avila J.   +6 more
europepmc   +1 more source

Bionic Microneedle Patch Inspired by Drosophila Tarsal Paws Boosts Healing in Bacterial Infectious Stomatitis

Advanced Science, EarlyView.
Microneedle suction cup patches, prepared using bionic Drosophila tarsal claws, can effectively treat bacterial infectious stomatitis by rapidly and efficiently leveraging multiple effects, including antibacterial and anti‐inflammatory properties, promotion of vasodilation, and active mechanical contraction of the wound.
Jiaqi Qin, Cewen Hu, Xiaohong Ran, Huajing Zeng, Jie Zhang, Bin Liu, Zengjie Fan   +6 more
wiley   +1 more source

The histone deacetylase inhibitor CT-101 flips the switch to fetal hemoglobin expression in sickle cell disease mice. [PDF]

PLoS One
Takezaki M, Li B, Xu H, Patel N, Lucas R, Cerbone RE, Koti S, Hendrick CL, Junker LH, Pace BS.   +9 more
europepmc   +1 more source