Results 101 to 110 of about 139,229 (304)

Experimental Mikulicz-Like Disease of the Lacrimal Gland, Induced by Repeated Subcutaneous Injections of 5-Hydroxytryptamine

open access: yes, 1968
A Mikulicz-like disease of the lacrimal glands occurred after six weekly subcutaneous injections of 10 mg of 5-hydroxytryptamine. The lacrimal glands of all experimental rats developed a dense lymphocytic infiltration that caused destruction of acinar ...
Alvin F. Gardner
core   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang   +17 more
wiley   +1 more source

Randomized clinical trial to assess pain and bruising in medicines administered by means of subcutaneous and intramuscular needle injection: Is it necessary to have needles changed?

open access: yesRevista Latino-Americana de Enfermagem
This clinical trial aimed at comparing the intensity of pain and bruising by subcutaneous and intramuscular injections using and retractable fixed syringes and needles and syringes with no needles combined, at a public hospital in Sao Paulo, for six ...
Luiz Carlos Ribeiro Lamblet   +4 more
doaj  

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni   +7 more
wiley   +1 more source

Duration of subcutaneous heparin injections : effect on bruising and pain.

open access: yes, 2000
Injection site-pain and bruising are common side effects of subcutaneous heparin injections. These adverse outcomes are problematic for both the patient and the nurse.
Chan, Harriet S. C.
core  

Body measurements and growth rate in male rats receiving multiple subcutaneous bolus injections of ASB20123 for 7 days.

open access: yes, 2019
Body measurements and growth rate in male rats receiving multiple subcutaneous bolus injections of ASB20123 for 7 days.
Hiroaki Maeda (1366338)   +10 more
core   +1 more source

Outpatient subcutaneous injection therapy : drug use problems with low-molecular-weight heparins and impact of pharmaceutical care [PDF]

open access: yes, 2012
Arterial and venous thromboses are important diseases associated with significant morbidity, mortality, and costs. To date, the orally taken vitamin K antagonists are, together with the parenterally administered heparins, still the most frequently used ...
Mengiardi, Seraina
core   +1 more source

Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato   +8 more
wiley   +1 more source

Intramuscular versus Subcutaneous Injections of Testosterone in Transgender Men

open access: yes, 2019
Hormone replacement therapy (HRT) is a common treatment for gender dysphoria, a condition where a person’s gender assigned at birth does not match their gender identify. For transgender men seeking to achieve virilization, HRT is included in the standard
Hum, Julia, Ph.D, Palmer, Adrian, OMS-1
core  

Tracking Spatiotemporal Extracellular Matrix Evolution and Tissue Fusion in 3D Microtissues via Click Chemistry‐Based Metabolic Labelling

open access: yesAdvanced Healthcare Materials, EarlyView.
Metabolic labeling of nascent proteins in 3D microtissue spheroids provides a powerful analytical approach for large‐scale tissue engineering. Incorporation of non‐canonical amino acids with fluorescent tagging enables spatiotemporal investigation of extracellular matrix deposition and its evolution during multicellular tissue development and fusion ...
Theresa Koenig   +3 more
wiley   +1 more source

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