Results 61 to 70 of about 1,445,553 (355)

Injections and Patient Satisfaction in Zulu-Speaking Patients

South African Family Practice, 2002
One of the main objectives in a consultation is for patients to leave the consulting room feeling satisfied with their consultation. Satisfied patients are more likely to remain with a physician, keep appointments, comply with treatment and refer other ...
H.F. Niebuhr, M.J. Whitfield
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Iatrogenic HIV transmission in South Africa: Evidence, estimates and moral perspectives

South African Family Practice, 2010
The risks of HIV transmission to patients exceed many health professionals’ expectations in South Africa. Non-vertical HIV transmission to children is more common in cases where adherence to infection control guidelines is generally poor.
Savanna R. Reid, Suraya Dawad, Anton A. van Niekerk   +2 more
doaj   +1 more source

Modeling CD4+ T cells dynamics in HIV-infected patients receiving repeated cycles of exogenous Interleukin 7 [PDF]

, 2016
Combination Antiretroviral Therapy (cART) succeeds to control viral replication in most HIV infected patients. This is normally followed by a reconstitution of the CD4$^+$ T cells pool; however, this does not happen for a substantial proportion of ...
Commenges, Daniel, Jarne, Ana, Levy, Yves, Prague, Mélanie, Thiébaut, Rodolphe   +4 more
core   +2 more sources

The formation of regular interarm magnetic fields in spiral galaxies

, 2015
Observations of regular magnetic fields in several nearby galaxies reveal magnetic arms situated between the material arms. The nature of these magnetic arms is a topic of active debate.
Beck, Rainer, Krause, Marita, Moss, David, Sokoloff, Dmitri, Stepanov, Rodion   +4 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

VYC-20L is Safe and Effective for Improving Volume and Aesthetic Appearance of the Nose in Chinese Adults

Clinical, Cosmetic and Investigational Dermatology, 2022
Dong Li,1 Jiaming Sun,2 Yuguang Zhang,3 Xiaojun Wang,4 Songlin Yang,5 Candice Harvey,6 Lijuan Zhang7 1Department of Plastic Surgery, Peking University Third Hospital, Beijing, People’s Republic of China; 2Depatment of Plastic Surgery, Union Hospital ...
Li D, Sun J, Zhang Y, Wang X, Yang S, Harvey C, Zhang L   +6 more
doaj  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Octreotide in the therapy of recurrent medulloblastomas [PDF]

Archive of Oncology, 2006
BACKGROUND: Recurrence of medulloblastoma appears after 30% to 40% of the surgeries. Different from primary medulloblastoma, in which five-year survival rate is 50%, the survival time of relapses much shorter and only 20% of the patients manage to ...
Stefanović Ivan, Stojanović Nebojša, Stojanov Dragan, Dimov Dragan   +3 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source