Results 51 to 60 of about 772,174 (280)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Sperm retrieval techniques in azoospermic patients: PESA, MESA, TESA, TESE and MICROTESE [PDF]

open access: yesEinstein (São Paulo), 2009
Azoospermia is defined as the absence of mature spermatozoa in semen analysis after centrifugation. The causes of azoospermia may be related to spermatogenesis defects and classified as non-obstructive azoospermia, or to the obstruction of the efferent ...
Marcelo Vieira, Sidney Glina
doaj  

Potential Toxic Effects of Different High Doses of Glutathione Injection: An Experimental Study [PDF]

open access: yesAin Shams Journal of Forensic Medicine and Clinical Toxicology
Background: Glutathione injections for skin whitening have been widely used recently incapricious dosing regimens with no scientific evidence. The overall safety data on injectableglutathione are scarce.
Nada Yousri   +3 more
doaj   +1 more source

Association of Mesoscale Auroral Structures and Breakups With Energetic Particle Injections at Geosynchronous Orbit

open access: yesFrontiers in Astronomy and Space Sciences, 2022
Geomagnetic substorms are associated with characteristic energetic particle injection signatures at geosynchronous orbit that are often dispersionless in both electrons and ions near the magnetic local time sector of auroral onset locations and are ...
M. G. Henderson 
doaj   +1 more source

An unfortunate injection [PDF]

open access: yesBMJ Case Reports, 2016
Intramuscular injection has been used to administer medications for more than a hundred years. However, despite our profession's long experience with intramuscular administration, preventable complications such as injection nerve palsies are still prevalent in developing countries. Injections account for one-fifth of all traumatic nerve injuries. These
Bhavik Sandip Shah   +3 more
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Advances in Drug and Vaccine Delivery for Low- and Middle-Income Healthcare Programs—The Case for Replacing Multi-Dose Vials with Prefilled Single-Dose Delivery Systems

open access: yesPharmacy
The transition toward wide-scale use of single-dose administration systems such as prefilled syringes has primarily occurred in high-income countries due to economic considerations.
Darin Zehrung, Michael J. Free
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Effectiveness of Platelet-Rich Plasma Injection in Rotator Cuff Tendinopathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

open access: yesDiagnostics, 2020
Background: To investigate the effectiveness of platelet-rich plasma (PRP) injection among patients with rotator cuff tendinopathy in comparison with sham injection, no injection, or physiotherapy alone.
Meng-Ting Lin   +2 more
doaj   +1 more source

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