Results 51 to 60 of about 724,211 (317)

The Effect of the Ventrogluteal Injection Training on the Knowledge Levels and Preferences of Health Professionals

Forbes Tıp Dergisi, 2020
INTRODUCTION: This study is aimed to determine the effect of ventrogluteal injection training on the health professionals' knowledge levels and preferences about the use of the ventroglu- teal region for intramuscular injections.
Ahu Çırlak, Nur Temiz, Merve Başol
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Ultrasound-Assisted Lumbar Interlaminar Epidural Dye Injection and Evaluation of Its Distribution by Anatomical Dissection

Frontiers in Medicine, 2019
Background: Epidural steroid injections are frequently used to treat lumbar radicular pain. However, the spread of a solute in the epidural space needs further elucidation.
Irina Evansa, Irina Evansa, Angelika Krumina, Anna Simonova, Viktorija Dzabijeva, Svetlana Fedorovica, Alla Hadunkina, Alla Hadunkina, Natalja Zlobina, Grigorijs Vabels, Eva Strike, Ludmila Viksna, Indulis Vanags   +12 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

On the compound Poisson risk model with periodic capital injections

, 2018
The analysis of capital injection strategy in the literature of insurance risk models (e.g. Pafumi, 1998; Dickson and Waters, 2004) typically assumes that whenever the surplus becomes negative, the amount of shortfall is injected so that the company can ...
Cheung, ECK ; https://orcid.org/, Yang, H, Cheung, ECK, Zhang, Z   +3 more
core   +1 more source

Intra-mesenteric steroids for steroid-refractory graft-versus-host disease in pediatric patients: A safe option

Biomédica: revista del Instituto Nacional de Salud
Introduction. Graft-versus-host disease is a serious complication after hematopoietic stem cell transplantation and is a major cause of death post-transplantation.
Ana M. Aristizábal, Lina P. Montaña, Jaiber Gutiérrez, Diego Medina, Alexis A. Franco, Eliana Manzi, Ángela Devia Zapata, Walter Mosquera   +7 more
doaj   +1 more source

Injections and Patient Satisfaction in Zulu-Speaking Patients

South African Family Practice, 2002
One of the main objectives in a consultation is for patients to leave the consulting room feeling satisfied with their consultation. Satisfied patients are more likely to remain with a physician, keep appointments, comply with treatment and refer other ...
H.F. Niebuhr, M.J. Whitfield
doaj   +1 more source

Injective and non-injective realizations with symmetry

Contributions to Discrete Mathematics, 2010
In this paper, we introduce a natural classification of bar and joint frameworks that possess symmetry. This classification establishes the mathematical foundation for extending a variety of results in rigidity, as well as infinitesimal or static rigidity, to frameworks that are realized with certain symmetries and whose joints may or may not be ...
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source