Results 51 to 60 of about 20,537 (194)

Integrated Nested Laplace Approximations (INLA)

open access: yes, 2019
This is a short description and basic introduction to the Integrated nested Laplace approximations (INLA) approach. INLA is a deterministic paradigm for Bayesian inference in latent Gaussian models (LGMs) introduced in Rue et al. (2009). INLA relies on a combination of analytical approximations and efficient numerical integration schemes to achieve ...
Martino, Sara, Riebler, Andrea
openaire   +2 more sources

Burden and Forecast of Early‐Onset Colorectal Cancer (1990–2038) in Five East Asian Populations: A Systematic Analysis Based on the GBD 2023 Study

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Early‐onset colorectal cancer (EO‐CRC) is increasing globally with substantial regional variation. We assessed epidemiological changes in EO‐CRC in five East Asian populations. Methods Using GBD 2023 data, we calculated age‐standardized incidence, prevalence, mortality, and DALY rates (ASIR, ASPR, ASMR, ASDR), counts, and average ...
Lili jin   +4 more
wiley   +1 more source

A general theory for preferential sampling in environmental networks

open access: yes, 2019
This paper presents a general model framework for detecting the preferential sampling of environmental monitors recording an environmental process across space and/or time.
Shaddick, Gavin   +2 more
core   +1 more source

Hemisphere‐Level Comparison of Climate‐Driven Humpback Whale Breeding Migrations to the Eastern Pacific Off Costa Rica

open access: yesEcology and Evolution, Volume 16, Issue 5, May 2026.
This study analyzed humpback whale occurrence off the Pacific coast of Costa Rica from 2001 to 2023, focusing on the Central America and Southeast Pacific Distinct Population Segments, using long‐term sightings and Bayesian time‐series and habitat models.
Lili Pelayo‐González   +6 more
wiley   +1 more source

Directed evolution and targeted mutagenesis to murinize listeria monocytogenes internalin A for enhanced infectivity in the murine oral infection model

open access: yesBMC Microbiology, 2010
Background Internalin A (InlA) is a critical virulence factor which mediates the initiation of Listeria monocytogenes infection by the oral route in permissive hosts.
Hill Colin   +3 more
doaj   +1 more source

Burden of Nutritional Deficiencies: A Systematic Analysis for the GBD 2021

open access: yesHealth Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Nutritional deficiencies (ND) remain a major global health challenge, significantly affecting population well‐being. As part of the Global Burden of Disease (GBD) study, we conducted a comprehensive assessment of the prevalence, incidence, mortality, and disability‐adjusted life years (DALYs) attributed to ND from 1990 to ...
Shuxiong Nong, Rui Deng, Xiuhua Zhang
wiley   +1 more source

The Majority of Genotypes of the Virulence Gene inlA Are Intact among Natural Watershed Isolates of Listeria monocytogenes from the Central California Coast.

open access: yesPLoS ONE, 2016
Internalin A is an essential virulence gene involved in the uptake of the foodborne pathogen Listeria monocytogenes into host cells. It is intact in clinical strains and often truncated due to Premature Stop Codons (PMSCs) in isolates from processed ...
Lisa Gorski   +4 more
doaj   +1 more source

Listeria monocytogenes internalin B activates junctional endocytosis to accelerate intestinal invasion. [PDF]

open access: yesPLoS Pathogens, 2010
Listeria monocytogenes (Lm) uses InlA to invade the tips of the intestinal villi, a location at which cell extrusion generates a transient defect in epithelial polarity that exposes the receptor for InlA, E-cadherin, on the cell surface.
Mickey Pentecost   +3 more
doaj   +1 more source

Latent Gaussian modeling and INLA: A review with focus on space-time applications [PDF]

open access: yes, 2016
Bayesian hierarchical models with latent Gaussian layers have proven very flexible in capturing complex stochastic behavior and hierarchical structures in high-dimensional spatial and spatio-temporal data.
Opitz, Thomas
core   +2 more sources

Epidemiological Features and Temporal Trends of Five Common Sexually Transmitted Infections Excluding HIV, 1990–2021: Findings From the Global Burden of Disease Study

open access: yesJournal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Sexually transmitted infections (STIs) remain a major global health threat. A comprehensive assessment of their epidemiological features and future trajectories is essential for informing targeted public health policies and achieving international control targets.
Baigong Feng   +5 more
wiley   +1 more source

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