Results 51 to 60 of about 20,209,781 (300)

Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation

open access: yesMediators of Inflammation, 2016
Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
Kathleen L. McCoy
doaj   +1 more source

Immune Function Genes, Genetics, and the Neurobiology of Addiction

open access: yesAlcohol Research, 2012
The neuroimmune system (i.e., the immune system and those components of the nervous system that help regulate immune responses), and in particular the innate immune system, play a role in the development of addictions, including alcoholism ...
Fulton T. Crews
doaj   +1 more source

Physiology and Pathology of Innate Immune Response Against Pathogens [PDF]

open access: yes, 2017
Pathogen infections are recognized by the immune system, which consists of two types of responses: an innate immune response and an antigen-specific adaptive immune response.
Contreras Cordero, Juan Francisco   +9 more
core   +1 more source

Memory and Specificity in the Insect Immune System: Current Perspectives and Future Challenges

open access: yesFrontiers in Immunology, 2017
The immune response of a host to a pathogen is typically described as either innate or adaptive. The innate form of the immune response is conserved across all organisms, including insects.
Dustin Cooper, Ioannis Eleftherianos
doaj   +1 more source

Systems Biology and Innate Immunity

open access: yesJournal of Innate Immunity, 2013
The innate immune system is the first line of host defense against invading microorganisms and is essential for maintenance of host health. The innate immune response is largely mediated by soluble host factors—such as complement—and phagocytic leukocytes.
Scott D, Kobayashi, Frank R, Deleo
openaire   +3 more sources

The immune system as drug target [PDF]

open access: yes, 2013
The immune system is perhaps the largest yet most diffuse and distributed somatic system in vertebrates. It plays vital roles in fighting infection and in the homeostatic control of chronic disease.
Flower, Darren R.
core   +1 more source

The innate immune system 'puzzle' [PDF]

open access: yesNature Immunology, 2006
Detecting pathogen invasion and regulating homeostatic processes are two essential functions of myriad non-Toll-like innate immune proteins.
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Development of the Innate Immune Response in NestlingTree Swallows (Tachycineta bicolor) [PDF]

open access: yes, 2009
The innate immune system provides an immediate, short term, first line of defense from pathogens; its appearance early in development in vertebrates is evidence of its critical importance.
Stambaugh, T.R.
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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