Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn +5 more
wiley +1 more source
Harnessing the innate immune system: a novel bispecific antibody targeting CD47 and CD24 for selective tumor clearance. [PDF]
Nan L +13 more
europepmc +1 more source
Innate Immune System in the Context of Radiation Therapy for Cancer. [PDF]
Boopathi E, Den RB, Thangavel C.
europepmc +1 more source
A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani +2 more
wiley +1 more source
The ADAMTS2 metalloproteinase inhibits tumor growth by regulating the innate immune system. [PDF]
Joannes L +14 more
europepmc +1 more source
Overcoming the immunogenicity challenges of enzyme‐mediated crosslinking, a flow‐through reactor utilizing SFNF‐HRP enables the continuous production of injectable hydrogels. This continuous platform ensures homogeneous crosslinking while minimizing residual HRP in the resulting hydrogels.
Ayari Miyawaki, Shinji Sakai
wiley +1 more source
The Interplay Between Therapeutic Self-Amplifying RNA and the Innate Immune System: Balancing Efficiency and Reactogenicity. [PDF]
Kunyk D +6 more
europepmc +1 more source
Organoids as Building Blocks for Adaptive and Resilient Biohybrid Robots
ABSTRACT Biohybrid robots combine engineered living tissues with synthetic materials and have emerged as a promising class of soft robotic systems capable of mimicking biological functions such as biodegradability, energy efficiency and flexible motions. By integrating biological and synthetic components, these systems leverage complementary properties
Antonia Georgopoulou
wiley +1 more source
Innate immune system for a crosstalk of sperm-egg-uterine epithelium towards fertility: Toll-like receptor 2 as a physiological sensor. [PDF]
Akthar I, Mansouri A, Miyamoto A.
europepmc +1 more source
The Dual Role of the Innate Immune System in the Effectiveness of mRNA Therapeutics. [PDF]
Muslimov A +6 more
europepmc +1 more source

