Results 41 to 50 of about 20,209,781 (300)
Innate and Adaptive Immune Responses Against Microsporidia Infection in Mammals
Frontiers in Microbiology, 2020 Microsporidia are obligate intracellular and eukaryotic pathogens that can infect immunocompromised and immunocompetent mammals, including humans. Both innate and adaptive immune systems play important roles against microsporidian infection.
Yinze Han +17 more
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Regulation of Adaptive Immunity by the Innate Immune System [PDF]
Science, 2010 Twenty years after the proposal that pattern recognition receptors detect invasion by microbial pathogens, the field of immunology has witnessed several discoveries that have elucidated receptors and signaling pathways of microbial recognition systems and how they control the generation of T and B lymphocyte–mediated immune responses.
Akiko, Iwasaki, Ruslan, Medzhitov
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The porcine innate immune system: an update. [PDF]
, 2014 Over the last few years, we have seen an increasing interest and demand for pigs in biomedical research. Domestic pigs (Sus scrofa domesticus) are closely related to humans in terms of their anatomy, genetics, and physiology, and often are the model of ...
Pasternak, A +10 more
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Determinants of innate immune responses to mycobacteria [PDF]
, 2012 Includes bibliographical references.Innate cells such as macrophages, monocytes, myeloid dendritic cells and granulocytes recognise mycobacteria and initiate immune responses such as phagocytosis, cytokine production and expression of maturation markers.
Shey, Muki Shehu
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Frontiers in Immunology, 2019 The immune system is composed of two subsystems—the innate immune system and the adaptive immune system. The innate immune system is the first to respond to pathogens and does not retain memory of previous responses.
Nicole C. Smith +2 more
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Virulence, 2021 Appropriate clearance of dead cells generated by apoptosis is critical to the development of multicellular organisms and tissue homeostasis. In mammals, the removal of apoptotic cell is mediated by polarized monocyte/macrophage populations of the innate ...
Jinlong Wan +4 more
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CD4+CD25+ TR cells suppress innate immune pathology through cytokine-dependent mechanisms [PDF]
, 2003 Copyright @ 2003 The Rockefeller University PressCD4+CD25+ regulatory T (TR) cells can inhibit a variety of autoimmune and inflammatory diseases, but the precise mechanisms by which they suppress immune responses in vivo remain unresolved.
Fiona Powrie +17 more
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Pathophysiology of Inflammatory Bowel Disease: Innate Immune System [PDF]
, 2023 Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause.
Gomez-Bris, Raquel +16 more
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Four Pathways Involving Innate Immunity in the Pathogenesis of Preeclampsia
Frontiers in Cardiovascular Medicine, 2015 The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE).
Kelsey R Bounds +2 more
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Frontiers in Immunology, 2023 The large majority of lymphocytes belong to the adaptive immune system, which are made up of B2 B cells and the αβ T cells; these are the effectors in an adaptive immune response.
Sebastian Joyce +3 more
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