Polysaccharide intercellular adhesin (PIA) protects Staphylococcus epidermidis against major components of the human innate immune system [PDF]
, 2004 Cuong Vuong +6 more
openalex +1 more source
Advanced Functional Materials, EarlyView.This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput +5 more
wiley +1 more source
Toll-like receptors and the host defense against microbial pathogens: bringing specificity to the innate-immune system [PDF]
, 2004 Mihai G. Netea +3 more
openalex +1 more source
Advanced Functional Materials, EarlyView.Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang +9 more
wiley +1 more source
Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system [PDF]
, 2004 Adrian Erlebacher +3 more
openalex +1 more source
Advanced Functional Materials, EarlyView.This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras +19 more
wiley +1 more source
If the ‘Adaptive’ Immune System Can Recognize a Significant Portion of the Pathogenic Universe to Which the ‘Innate’ Immune System is Blind, Then… [PDF]
, 2004 Melvin Cohn
openalex +1 more source
Asymptomatic hyperuricaemia: a silent activator of the innate immune system
Nature Reviews Rheumatology, 2019 L. Joosten +3 more
semanticscholar +1 more source
Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury
Advanced Functional Materials, EarlyView.After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen +9 more
wiley +1 more source
Structure and metabolism of peptidoglycan and molecular requirements allowing its detection by the Drosophila innate immune system [PDF]
, 2005 Dominique Mengin‐Lecreulx +1 more
openalex +1 more source