Results 161 to 170 of about 1,083,097 (291)

HGF/c‐Met Axis‐Targeted Nanotherapy via GSH‐Responsive Polymer Platforms Suppresses Uveal Melanoma Metastasis

Advanced Healthcare Materials, EarlyView.
To suppress uveal melanoma metastasis (UM), the GSH‐responsive polymer named NP@Oxa/Criz has been successfully prepared. NP@Oxa/Criz selectively accumulates in UM tumors, targeting HGF/c‐Met Axis to undermine the stemness and metastasis of UM while triggering immunogenic cell death through DAMPs release to boost anti‐tumor immunity.
Hui Tao, Hanhan Liu, Hanchen Zhang, Hong Ren, Binyu Wen, Jing Zhang, Jiaqi Du, Ziyi Cai, Zhihong Deng   +8 more
wiley   +1 more source

Activation of the Drosophila innate immune system accelerates growth in cooperation with oncogenic Ras. [PDF]

PLoS Biol
Brutscher F, Germani F, Hausmann G, Jutz L, Basler K.   +4 more
europepmc   +1 more source

Structure and metabolism of peptidoglycan and molecular requirements allowing its detection by the Drosophila innate immune system [PDF]

, 2005
Dominique Mengin‐Lecreulx, Bruno Lemaître   +1 more
openalex   +1 more source

Development of Itaconate Polymers Microparticles for Intracellular Regulation of Pro‐Inflammatory Macrophage Activation

Advanced Healthcare Materials, EarlyView.
This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth, Zachary S.C.S. Froom, Natasha D. Osborne, Christian N. Rempe, Brenden Wheeler, Kyle Medd, Neal I. Callaghan, Huikang Qian, Abhinav P. Acharya, Carlie Charron, Locke Davenport Huyer   +10 more
wiley   +1 more source

Inflammatory Bowel Disease from the Perspective of Newer Innate Immune System Biomarkers. [PDF]

Gastrointest Disord (Basel)
Tobi M, Antaki F, Rambus M, Hellman J, Hatfield J, Fligiel S, McVicker B.   +6 more
europepmc   +1 more source

Heatstroke-induced acute kidney injury and the innate immune system. [PDF]

Front Med (Lausanne), 2023
Goto H, Kinoshita M, Oshima N.
europepmc   +1 more source

Dendritic Cell Surface Calreticulin Is a Receptor for NY-ESO-1: Direct Interactions between Tumor-Associated Antigen and the Innate Immune System [PDF]

, 2006
Gang Zeng, Michael E. Aldridge, Xiaoli Tian, Daniel Seiler, Xiaolong Zhang, Yusheng Jin, Jianyu Rao, Weidong Li, Dequan Chen, Marlyn P. Langford, Chris Duggan, Arie S. Belldegrun, Steven M. Dubinett   +12 more
openalex   +1 more source

Imine Crosslinked, Injectable, and Self‐Healing Fucoidan Hydrogel with Immunomodulatory Properties

Advanced Healthcare Materials, EarlyView.
This study develops an injectable fucoidan‐based hydrogel with tunable properties for tissue engineering. By oxidizing fucoidan (OFu) to introduce aldehydes, imine crosslinks are formed with amine‐containing polymers, enabling self‐healing, injectability, and long‐term stability (≥28 days). The OFu‐gelatin hydrogel demonstrated biocompatibility, immune‐
Asma Talib Qureshi, Shajia Afrin, Saad Asim, Muhammad Rizwan   +3 more
wiley   +1 more source

Caspase-8: Arbitrating Life and Death in the Innate Immune System. [PDF]

Cells
Gupta S, Lopez MA, Ektesabi AM, Tsoporis JN, Vaswani CM, Gandhi SY, Fairn GD, Dos Santos CC, Marshall JC.   +8 more
europepmc   +1 more source

Advances in proteomics: characterization of the innate immune system after birth and during inflammation. [PDF]

Front Immunol, 2023
Bennike TB.
europepmc   +1 more source