Results 41 to 50 of about 19,688,530 (256)

Pathophysiology of Inflammatory Bowel Disease: Innate Immune System [PDF]

open access: yes, 2023
Inflammatory bowel disease (IBD), comprising Crohn’s disease (CD) and ulcerative colitis (UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause.
Gomez-Bris, Raquel   +16 more
core   +1 more source

Defective apoptotic cell clearance activates innate immune response to protect Caenorhabditis elegans against pathogenic bacteria

open access: yesVirulence, 2021
Appropriate clearance of dead cells generated by apoptosis is critical to the development of multicellular organisms and tissue homeostasis. In mammals, the removal of apoptotic cell is mediated by polarized monocyte/macrophage populations of the innate ...
Jinlong Wan   +4 more
doaj   +1 more source

CD4+CD25+ TR cells suppress innate immune pathology through cytokine-dependent mechanisms [PDF]

open access: yes, 2003
Copyright @ 2003 The Rockefeller University PressCD4+CD25+ regulatory T (TR) cells can inhibit a variety of autoimmune and inflammatory diseases, but the precise mechanisms by which they suppress immune responses in vivo remain unresolved.
Fiona Powrie   +17 more
core   +1 more source

Four Pathways Involving Innate Immunity in the Pathogenesis of Preeclampsia

open access: yesFrontiers in Cardiovascular Medicine, 2015
The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE).
Kelsey R Bounds   +2 more
doaj   +1 more source

Die Kämpfe únd schláchten—the struggles and battles of innate-like effector T lymphocytes with microbes

open access: yesFrontiers in Immunology, 2023
The large majority of lymphocytes belong to the adaptive immune system, which are made up of B2 B cells and the αβ T cells; these are the effectors in an adaptive immune response.
Sebastian Joyce   +3 more
doaj   +1 more source

Bone and the Innate Immune System [PDF]

open access: yes, 2014
The immune system and bone are intimately linked with significant physical and functionally related interactions. The innate immune system functions as an immediate response system to initiate protections against local challenges such as pathogens and ...
Nakamura, Mary C, Charles, Julia F
core   +1 more source

Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation

open access: yesMediators of Inflammation, 2016
Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
Kathleen L. McCoy
doaj   +1 more source

Physiology and Pathology of Innate Immune Response Against Pathogens [PDF]

open access: yes, 2017
Pathogen infections are recognized by the immune system, which consists of two types of responses: an innate immune response and an antigen-specific adaptive immune response.
Contreras Cordero, Juan Francisco   +9 more
core   +1 more source

Memory and Specificity in the Insect Immune System: Current Perspectives and Future Challenges

open access: yesFrontiers in Immunology, 2017
The immune response of a host to a pathogen is typically described as either innate or adaptive. The innate form of the immune response is conserved across all organisms, including insects.
Dustin Cooper, Ioannis Eleftherianos
doaj   +1 more source

The immune system as drug target [PDF]

open access: yes, 2013
The immune system is perhaps the largest yet most diffuse and distributed somatic system in vertebrates. It plays vital roles in fighting infection and in the homeostatic control of chronic disease.
Flower, Darren R.
core   +1 more source

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