Results 11 to 20 of about 19,688,530 (256)

The innate immune system: A double-edged sword. [PDF]

open access: yesPLoS Biology
Innate immunity serves as a crucial surveillance framework, but can be exploited to facilitate tumor progression. Two new PLOS Biology studies independently show how premalignant cells can exploit Toll-NF-κB signaling, in concert with oncogenic Ras, to ...
Ditte S Andersen, Julien Colombani
doaj   +2 more sources

Antimicrobial Power of Organic Acids and Nature-Identical Compounds against Two Vibrio spp.: An In Vitro Study

open access: yesMicroorganisms, 2021
Vibrosis is one of the major threats in aquaculture farming, and due to the increasing antimicrobial resistance of different Vibrio species, there is an urgent need to replace conventional treatments with more sustainable solutions.
Barbara Rossi   +6 more
doaj   +1 more source

Leprosy and Immune System An Insight into the Innate Immune System [PDF]

open access: yes, 2021
Innate immunity is a host immune mechanism to defend itself promptly. It includes physical and chemical barriers, cells in the circulation and tissues, several plasma proteins, and immune cells constituting phagocytic cells (monocytes/macrophages and ...
Budiamal, S   +2 more
core   +1 more source

Innate immune sensors for detecting nucleic acids during infection

open access: yesJournal of Laboratory Medicine, 2022
Innate immune receptors detect nucleic acids, such as viruses, and initiate an immune response by secreting interferon (IFN) and regulating IFN-stimulated genes (ISG).
Ghoreshi Zohreh-alsadat   +4 more
doaj   +1 more source

Innate Immune Responses to Influenza Virus Infections in the Upper Respiratory Tract

open access: yesViruses, 2021
The innate immune system is the host’s first line of immune defence against any invading pathogen. To establish an infection in a human host the influenza virus must replicate in epithelial cells of the upper respiratory tract. However, there are several
Edin J. Mifsud, Miku Kuba, Ian G. Barr
doaj   +1 more source

ADHESION OF PATHOGENIC BACTERIA TO POLYSTYRENE, SKIN AND GUT MUCUS OF GILTHEAD SEABREAM, INFECTIOUS CAPACITY AND ANTIBIOTICS SUSCEPTIBILITY

open access: yesBoletim do Instituto de Pesca, 2019
Linking proprieties of adhesion, infectious capacities and antibiotic resistance of pathogen bacteria could help to treat fish diseases. Adhesions of ten fish pathogenic bacteria were tested in microtiter plates vacant, coated with skin or gut mucus ...
Said Ben Hamed   +5 more
doaj   +1 more source

Engineering physical microenvironments to study innate immune cell biophysics

open access: yesAPL Bioengineering, 2022
Innate immunity forms the core of the human body's defense system against infection, injury, and foreign objects. It aims to maintain homeostasis by promoting inflammation and then initiating tissue repair, but it can also lead to disease when ...
Nikita Kalashnikov, Christopher Moraes
doaj   +1 more source

Chronic wounds alter the proteome profile in skin mucus of farmed gilthead seabream

open access: yesBMC Genomics, 2017
Background Skin and its mucus are known to be the first barrier of defence against any external stressors. In fish, skin wounds frequently appear as a result of intensive culture and also some diseases have skin ulcers as external clinical signs. However,
Héctor Cordero   +3 more
doaj   +1 more source

Innate Immune System Activation and Neuroinflammation in Down Syndrome and Neurodegeneration: Therapeutic Targets or Partners?

open access: yesFrontiers in Aging Neuroscience, 2021
Innate immune system activation and inflammation are associated with and may contribute to clinical outcomes in people with Down syndrome (DS), neurodegenerative diseases such as Alzheimer’s disease (AD), and normal aging.
Md. Mahiuddin Ahmed   +17 more
doaj   +1 more source

Fish Granzyme A Shows a Greater Role Than Granzyme B in Fish Innate Cell-Mediated Cytotoxicity

open access: yesFrontiers in Immunology, 2019
Granzymes (Gzm) are serine proteases, contained into the secretory granules of cytotoxic cells, responsible for the cell-mediated cytotoxicity (CMC) against tumor cells and intracellular pathogens such as virus and bacteria.
Elena Chaves-Pozo   +8 more
doaj   +1 more source

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