Results 221 to 230 of about 1,512,579 (348)

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Recognition of Endogenous Nucleic Acids by the Innate Immune System.

Immunity, 2016
Axel Roers, Björn Hiller, V. Hornung
semanticscholar   +1 more source

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source

Activation of the Drosophila innate immune system accelerates growth in cooperation with oncogenic Ras. [PDF]

PLoS Biol
Brutscher F, Germani F, Hausmann G, Jutz L, Basler K.   +4 more
europepmc   +1 more source

Heatstroke-induced acute kidney injury and the innate immune system. [PDF]

Front Med (Lausanne), 2023
Goto H, Kinoshita M, Oshima N.
europepmc   +1 more source

Targeting the Innate Immune System as Immunotherapy for Acute Myeloid Leukemia [PDF]

, 2015
Emily Curran, Leticia Corrales, Justin Kline   +2 more
openalex   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Inflammatory Bowel Disease from the Perspective of Newer Innate Immune System Biomarkers. [PDF]

Gastrointest Disord (Basel)
Tobi M, Antaki F, Rambus M, Hellman J, Hatfield J, Fligiel S, McVicker B.   +6 more
europepmc   +1 more source

EFFECTS OF PROLINE-RICH PEPTIDES OF THE INNATE IMMUNE SYSTEM ON DRUG-RESISTANT BACTERIAL STRAINS

, 2018
Maria S. Zharkova, P. M. Kopeykin, Г. Е. Афиногенов, Д. С. Орлов, A. Yu. Artamonov, K. E. Safiullina, Maria S. Sukhareva, Elena Tsvetkova, B. L. Milman, А. Г. Афиногенова, О. В. Шамова   +10 more
openalex   +2 more sources

The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system [PDF]

, 2006
Peter G. Barlow, Yuexin Li, Thomas S. Wilkinson, Dawn M. E. Bowdish, Y. Elaine Lau, Céline Cosseau, Christopher Haslett, A. John Simpson, Robert E. W. Hancock, Donald J. Davidson   +9 more
openalex   +1 more source