The ADAMTS2 metalloproteinase inhibits tumor growth by regulating the innate immune system. [PDF]
Joannes L+14 more
europepmc +1 more source
Fishing Innate Immune System Properties through the Transcriptomic Single-Cell Data of Teleostei. [PDF]
Bobrovskikh AV+2 more
europepmc +1 more source
Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson+12 more
wiley +1 more source
Dendritic Cell Surface Calreticulin Is a Receptor for NY-ESO-1: Direct Interactions between Tumor-Associated Antigen and the Innate Immune System [PDF]
Gang Zeng+12 more
openalex +1 more source
Activation of the Drosophila innate immune system accelerates growth in cooperation with oncogenic Ras. [PDF]
Brutscher F+4 more
europepmc +1 more source
Immunotherapies inducing immunogenic cell death in cancer: insight of the innate immune system. [PDF]
Calvillo-Rodríguez KM+4 more
europepmc +1 more source
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput+5 more
wiley +1 more source
Use of Early Passage Fetal Intestinal Epithelial Cells in Semi–High-Throughput Screening Assays: An Approach to Identify New Innate Immune System Adjuvants [PDF]
Diana Buckner+5 more
openalex +1 more source
Biological significance of extracellular vesicles in innate immune system. [PDF]
Jadamba B, Park J, Lee H.
europepmc +1 more source
Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen+9 more
wiley +1 more source