Results 241 to 250 of about 1,613,203 (345)

Targeting the innate immune system in pediatric and adult AML. [PDF]

Leukemia
Perzolli A, Koedijk JB, Zwaan CM, Heidenreich O.   +3 more
europepmc   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Function of immune cells and effector molecules of the innate immune system in the establishment and maintenance of pregnancy in mammals - A review. [PDF]

Anim Biosci
Lee S, Yoo I, Cheon Y, Choi E, Kim S, Ka H.   +5 more
europepmc   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

The impact of trauma relevant concentrations of prostaglandin E₂ on the anti-microbial activity of the innate immune system. [PDF]

Front Immunol
Nicholson T, Belli A, Lord JM, Hazeldine J.   +3 more
europepmc   +1 more source

Recognition of tumors by the innate immune system and natural killer cells.

Advances in Immunology, 2014
A. Marcus, Benjamin G. Gowen, Thornton W. Thompson, A. Iannello, M. Ardolino, W. Deng, Lin Wang, N. Shifrin, D. Raulet   +8 more
semanticscholar   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Editorial: Pathogenic aspects of the innate immune system of the kidney. [PDF]

Front Med (Lausanne)
Oda T, Zeng R, Nakashima H.
europepmc   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Gliotoxin elicits immunotoxicity in the early innate immune system of ducks. [PDF]

Poult Sci
Wei Z, Jin Q, Liu W, Liu T, He K, Jin Z, Chen M, Jiang Y, Qian Y, Hong H, Zhang D, Liu Q, Yang Z, Li Q.   +13 more
europepmc   +1 more source