Results 261 to 270 of about 1,265,061 (383)

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

Advanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche, Ségolène Ladaigue, Giacomo Gropplero, Nicolas Zimmermann, Martin Nurmik, Irina Veith, Manh‐Louis Nguyen, Solenn Brosseau, Nicolas Poté, Pierre Mordant, Arnaud Roussel, Fathia Mami‐Chouaib, Fatima Mechta‐Grigoriou, Gérard Zalcman, Fabrice Soncin, Stéphanie Descroix, Maria Carla Parrini   +16 more
wiley   +1 more source

Brucella requires a functional Type IV secretion system to elicit innate immune responses in mice [PDF]

, 2007
Christelle M. Roux, Hortensia G. Rolán, Renato L. Santos, Phillip D. Beremand, Terry L. Thomas, L. Garry Adams, Renée M. Tsolis   +6 more
openalex   +1 more source

Predicting viral proteins that evade the innate immune system: a machine learning-based immunoinformatics tool. [PDF]

BMC Bioinformatics
Beltrán JF, Belén LH, Yáñez AJ, Jimenez L.   +3 more
europepmc   +1 more source

On the path to predicting immune responses in the lung: Modeling the pulmonary innate immune system at the air-liquid interface (ALI). [PDF]

Eur J Pharm Sci, 2023
Graf J, Trautmann-Rodriguez M, Sabnis S, Kloxin AM, Fromen CA.   +4 more
europepmc   +1 more source

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

Nature, 2005
S. Gasser, S. Orsulic, E. Brown, D. Raulet   +3 more
semanticscholar   +1 more source

Synthetic Bilirubin‐Based Nanomedicine Protects Against Renal Ischemia/Reperfusion Injury Through Antioxidant and Immune‐Modulating Activity

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan, Hyunjin Kim, Bomin Kim, Honglin Piao, Joon Young Jang, Tae Kyeom Kang, Wook‐Bin Lee, Dohyeon Kim, Seunghyun Jo, Duckhyang Shin, Sharif MD Abuzar, Myung L. Kim, Jaeseok Yang, Sangyong Jon   +13 more
wiley   +1 more source

InnateDB: facilitating systems‐level analyses of the mammalian innate immune response [PDF]

, 2008
David J. Lynn, Geoffrey L. Winsor, Calvin C. Chan, Nicolas Richard, Matthew R. Laird, Aaron Barsky, Jennifer L. Gardy, Fiona Roche, Timothy H.W. Chan, Naisha Shah, Raymond Lo, Misbah Naseer, Jaimmie Que, Melissa Yau, M. Acab, Dan Tulpan, Matthew D. Whiteside, Avinash Chikatamarla, Bernadette Mah, Tamara Munzner, Karsten Hokamp, Robert E. W. Hancock, Fiona S. L. Brinkman   +22 more
openalex   +1 more source

The Liver X Receptor Promotes Immune Homeostasis via Controlled Activation of the Innate Immune System in the Liver. [PDF]

Biomolecules
Nakashima H, Kearney BM, Kinoshita M.
europepmc   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

The impact of trauma relevant concentrations of prostaglandin E₂ on the anti-microbial activity of the innate immune system. [PDF]

Front Immunol
Nicholson T, Belli A, Lord JM, Hazeldine J.   +3 more
europepmc   +1 more source