EPHA5 regulates antifungal innate immunity by phosphorylating EPHB2 and Dectin-1. [PDF]
Gao R+12 more
europepmc +1 more source
Activation of Innate Immunity in Nonhuman Primates Following Intraportal Administration of Adenoviral Vectors [PDF]
Michael A. Schnell+10 more
openalex +1 more source
Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin
Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis+6 more
wiley +1 more source
Mediators of Innate Immunity That Target Immature, But Not Mature, Dendritic Cells Induce Antitumor Immunity When Genetically Fused with Nonimmunogenic Tumor Antigens [PDF]
Arya Biragyn+7 more
openalex +1 more source
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail+3 more
wiley +1 more source
Innate immunity, therapeutic targets and monoclonal antibodies in SARS-CoV-2 infection. [PDF]
Nazir M+9 more
europepmc +1 more source
Endocytosed HSP60s Use Toll-like Receptor 2 (TLR2) and TLR4 to Activate the Toll/Interleukin-1 Receptor Signaling Pathway in Innate Immune Cells [PDF]
R. Martin Vabulas+6 more
openalex +1 more source
Imaging pH in a live rabbit at the surface of a sensor‐coated titanium plate using X‐ray excited luminescent chemical imaging (XELCI). A raster scanning X‐ray beam generates radioluminescence from a spot on the sensor, and the luminescence passes through the tissue and is collected at two wavelengths to determine local pH.
Unaiza Uzair+6 more
wiley +1 more source
The role of dendritic cells in the innate immune system
Georgina J. Clark+6 more
openalex +1 more source
Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: Regulatory role in the innate immune response [PDF]
Robert A. Mitchell+6 more
openalex +1 more source