Results 231 to 240 of about 604,934 (370)

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

open access: yesAdvanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle   +9 more
wiley   +1 more source

Effects of Benzalkonium Chloride on Innate Immunity Physiology of the Human Nasal Mucosa In Vivo [PDF]

open access: bronze, 2000
Torgeir Storaas   +5 more
openalex   +1 more source

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

open access: yesAdvanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu   +4 more
wiley   +1 more source

T cell receptor-dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity [PDF]

open access: bronze, 2000
Jack F. Bukowski   +6 more
openalex   +1 more source

Engineering Magnetotactic Bacteria as Medical Microrobots

open access: yesAdvanced Materials, EarlyView.
Magnetotactic bacteria (MTB) are living microorganisms that produce magnetosomes for navigation using the Earth's geomagnetic field. Their built‐in magnetic components, along with their intrinsic and/or modified biological functions, make them one of the most promising platforms for making future living and programmable microrobots.
Jiaqi Wang   +9 more
wiley   +1 more source

Cell-autonomous innate immunity by proteasome-derived defence peptides. [PDF]

open access: yesNature
Goldberg K   +29 more
europepmc   +1 more source

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