Results 231 to 240 of about 742,081 (332)

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Oomycetes manipulate plant innate immunity through galacturonide oxidases. [PDF]

Nat Commun
Welsh LRJ, Avrova AO, Besser K, Kirkbride T, Botelho Machado C, Hatton NE, Gomez LD, Fascione MA, Cartwright J, Boevink PC, Denby K, Cannella D, McQueen-Mason SJ, Whisson SC, Sabbadin F.   +14 more
europepmc   +1 more source

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

The role of innate immunity, antibiotics, and bacteriophages in the course of bacterial infections and their treatment. [PDF]

Proc Natl Acad Sci U S A
Berryhill BA, Gil-Gil T, Witzany C, Goldberg DA, Vega NM, Regoes RR, Levin BR.   +6 more
europepmc   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source

Interferon-stimulated circHOMER1 attenuates antiviral innate immunity. [PDF]

mBio
Zhang A, Yao R, Geng S, Wang H, Tang R-C, Yu H, Xu R, Chen H-Y, Zhou Y, Zhang L, Zhang J.   +10 more
europepmc   +1 more source

LBP, CD14, TLR4 and the murine innate immune response to a peritoneal Salmonella infection [PDF]

, 2001
Martin Bernheiden, Jan-Michael Heinrich, Gabriela Minigo, Christine Schütt, Felix Stelter, Mason W. Freeman, Douglas T. Golenbock, Robert Smail Jack   +7 more
openalex   +1 more source

Guided Bone Regeneration Membrane Materials Loaded with Chimeric Nanovesicles Promote Early Bone Defect Regeneration

Advanced Healthcare Materials, EarlyView.
Early bone regeneration is challenged by poor osteogenic microenvironments. We developed a novel guided bone regeneration (GBR) membrane: a plasma‐treated polycaprolactone (PT‐PCL) electrospun nanofiber functionalized with ultrasound sequentially extruded stromal vascular fraction chimeric vesicles (USE‐SCNVs). USE‐SCNVs require less equipment, enhance
Yufan Zhang, Yaqiong Wang, Xiaona Ning, Guichu Yue, Wenhui Zhang, Yicheng Chen, Xuelian Jia, Yu Zhang, Xiao Zhang, Zihan Lu, Simin Zhu, Fuwei Liu, Yong Zhao, Liang Kong   +13 more
wiley   +1 more source

The cGAS‒STING pathway in colorectal cancer: bridging innate immunity and therapeutic strategies. [PDF]

J Exp Clin Cancer Res
Li WJ, Dong GH, Bi Y, Han YY, Sun LL, Wang T, Lin ZH, Ren XS.   +7 more
europepmc   +1 more source

Bone‐Derived dECM Hydrogels Support Tunable Microenvironments for In Vitro Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A tunable methacrylated decellularized bone matrix hydrogel (dECM‐MA) is developed to support 3D culture of human osteoblasts. The hydrogel preserves bone‐specific ECM cues and allows precise control over mechanical properties. This system provides a customizable platform for studying osteogenic differentiation and modeling bone tissue environments for
Minne Dekker, Luke Hipwood, Akhilandeshwari Ravichandran, Dietmar W. Hutmacher, Christoph Meinert, Jacqui McGovern   +5 more
wiley   +1 more source