Results 241 to 250 of about 358,690 (312)

The antibacterial arm of the Drosophila innate immune response requires an IκB kinase

, 2001
Yiran Lu, Louisa P. Wu, Kathryn V. Anderson   +2 more
openalex   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

Insects fight low-dose infections with terminal investment, not innate immunity

Liu J, Priest NK.
europepmc   +1 more source

Malnutrition Alters the Innate Immune Response and Increases Early Visceralization followingLeishmania donovaniInfection

, 2001
Gregory M. Anstead, Bysani Chandrasekar, Weiguo Zhao, Jue Yang, Luis E. Pérez, Peter C. Melby   +5 more
openalex   +1 more source

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum, Abhirami Thumsi, Kara Dunn, Lindsey Druschel, Sierra Chimene, David Flores Prieto, Amberlyn Simmons, Shivani Mantri, Arezoo Esrafili, Srivatsan J. Swaminathan, Mytreyi Trivedi, Shreya Anandan, Crystal Willingham, Alondra Davila, Sahil Inamdar, Joslyn L. Mangal, Abhirami P. Suresh, Niveda M. Kasthuri, Madan Mohan Chandra Sekhar Jaggarapu, Nicole Appel, Taravat Khodaei, Nathan D. Ng, Alison Sundem, Sanmoy Pathak, George Bjorklund, Jason Newbern, Jeffrey Capadona, Sarah E. Stabenfeldt, Abhinav P. Acharya   +28 more
wiley   +1 more source

Editorial: Enhancing innate immunity in combination therapy for solid tumors. [PDF]

Front Immunol
Pejoski D.
europepmc   +1 more source

The 2.0-Å crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems

, 2001
Norman Kairies, Hans‐Georg Beisel, Pablo Fuentes‐Prior, Ryoko Tsuda, Tatsushi Muta, Sadaaki Iwanaga, Wolfram Bode, Robert Huber, Shun-ichiro Kawabata   +8 more
openalex   +1 more source

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

AUP1 and UBE2G2 complex targets STING signaling and regulates virus-induced innate immunity. [PDF]

mBio
Wang X-T, Zhu X, Lian Z-H, Liu Q, Yan H-H, Qiu Y, Ge X-Y.   +6 more
europepmc   +1 more source