Results 241 to 250 of about 358,690 (312)
The antibacterial arm of the Drosophila innate immune response requires an IκB kinase
Yiran Lu+2 more
openalex +1 more source
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail+3 more
wiley +1 more source
Insects fight low-dose infections with terminal investment, not innate immunity
Liu J, Priest NK.
europepmc +1 more source
Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum+28 more
wiley +1 more source
Editorial: Enhancing innate immunity in combination therapy for solid tumors. [PDF]
Pejoski D.
europepmc +1 more source
Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani+4 more
wiley +1 more source
AUP1 and UBE2G2 complex targets STING signaling and regulates virus-induced innate immunity. [PDF]
Wang X-T+6 more
europepmc +1 more source