Results 281 to 290 of about 604,934 (370)

Expression of innate immunity genes in human hematopoietic stem/progenitor cells - single cell RNA-seq analysis. [PDF]

Front Immunol
Jarczak J, Thetchinamoorthy K, Wierzbicka D, Bujko K, Ratajczak MZ, Kucia M.   +5 more
europepmc   +1 more source

Sustained Vaccine Exposure Elicits More Rapid, Consistent, and Broad Humoral Immune Responses to Multivalent Influenza Vaccines

Advanced Science, EarlyView.
This work presents an injectable polymer‐nanoparticle hydrogel depot platform for delivering multivalent influenza vaccines which induces stronger and more durable immune responses. The technology provides broader protection, including against heterologous and potential pandemic strains (H5N1, H7N9, H9N2), and enhances the effectiveness of commercial ...
Olivia M. Saouaf, Ben S. Ou, Ye Eun Song, Joshua J. Carter, Jerry Yan, Carolyn K. Jons, Christopher O. Barnes, Eric A. Appel   +7 more
wiley   +1 more source

Impairment of Innate Immunity and Depletion of Vaccine-Induced Memory B and T Cells in the Absence of the Spleen. [PDF]

Am J Hematol
Bordoni V, Cinicola BL, Piano Mortari E, Castilletti C, Guarracino F, Albano C, Accordini S, Baban A, Di Sabatino A, Rossi CM, Lenti MV, Zicari AM, Cirelli R, Spada M, Forni GL, Quinti I, Algeri M, Casale M, Perrotta S, Locatelli F, Agrati C, Carsetti R.   +21 more
europepmc   +1 more source

Metabolic‐Immune Suppression Mediated by the SIRT1‐CX3CL1 Axis Induces Functional Enhancement of Regulatory T Cells in Colorectal Carcinoma

Advanced Science, EarlyView.
This study discovers that SIRT1, a hub gene involved in glucolipid metabolic conversion in colorectal carcinoma (CRC), stimulates CX3CL1 secretion in CRC cells by activating FOXO1. The CX3CL1‐CX3CR1 signaling promotes the differentiation of TCF7+ regulatory T cells (Tregs) into an enhanced immunosuppressive TNFRSF9+ Treg phenotype.
Ruiyang Zi, Xiang Zhao, Limei Liu, Yijie Wang, Rui Zhang, Zhiheng Bian, Haoran Jiang, Taorui Liu, Yixin Sun, Han Peng, Xuesong Wang, Fanghao Lu, Chao Zhang, Fan Zhang, Qing Qin, Houjie Liang, Jianjun Li, Zhihao Wei, Yan Dong   +18 more
wiley   +1 more source

Insects fight low-dose infections with terminal investment, not innate immunity

Liu J, Priest NK.
europepmc   +1 more source

The Unusual Role of Ribonuclease L in Innate Immunity. [PDF]

Wiley Interdiscip Rev RNA
Karasik A, Guydosh NR.
europepmc   +1 more source

INNATE IMMUNITY: UPREGULATION OF MULTIPLE CHEMOKINES AND CYTOKINES IN MURINE CARDIAC ALLOGRAFT RECIPIENTS DEFICIENT IN T AND B LYMPHCYTES.

, 2000
Michael Buckley, Min Xu, Yunsheng Wang, Laura Tessmer, Luhua Shu, Diana O. Perkins   +5 more
openalex   +1 more source

Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis

Advanced Science, EarlyView.
An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Zhihua Ou, Li Li, Peidi Ren, Ting‐Ting Zhou, Fan He, Jialing Chen, Huimin Cai, Xiumin Han, Yao‐Dong Wu, Jiandong Li, Xiu‐Rong Li, Qiming Tan, Wenhui Li, Qi Chen, Nian‐Zhang Zhang, Xiuju He, Wei‐Gang Chen, Yanping Zhao, Jiwen Sun, Qian Zhang, Yan‐Tao Wu, Yingan Liang, Jie You, Guohai Hu, Xue‐Qi Tian, Sha Liao, Bao‐Quan Fu, Ao Chen, Xue‐Peng Cai, Huanming Yang, Jian Wang, Xin Jin, Xun Xu, Wan‐Zhong Jia, Junhua Li, Hong‐Bin Yan   +35 more
wiley   +1 more source

A secreted helminth microRNA suppresses gastrointestinal cell differentiation required for innate immunity. [PDF]

Front Immunol
Perez MG, Gillan V, Anderson WM, Gerbe F, Herbert F, McNeilly TN, Maizels RM, Jay P, Devaney E, Britton C.   +9 more
europepmc   +1 more source

Targeting Decidual CD16+ Immune Cells with Exosome‐Based Glucocorticoid Nanoparticles for Miscarriage

Advanced Science, EarlyView.
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang, Zhinang Yin, Yanqiong Shen, Gang Feng, Fangfang Dai, Dongyong Yang, Zhimin Deng, Jing Yang, Ruizhi Chen, Leifeng Yang, Xian Chen, Qing Sun, Chunyu Huang, Yanxiang Cheng, Hongbing Deng, Lianghui Diao, Longfei Li, Tailang Yin   +17 more
wiley   +1 more source