Results 31 to 40 of about 2,613,171 (336)

New insights into the evasion of host innate immunity by Mycobacterium tuberculosis

open access: yesCellular & Molecular Immunology, 2020
Mycobacterium tuberculosis (Mtb) is an extremely successful intracellular pathogen that causes tuberculosis (TB), which remains the leading infectious cause of human death.
Qiyao Chai, Lin Wang, C. Liu, Baoxue Ge
semanticscholar   +1 more source

Innate immune defects in HIV permissive cell lines. [PDF]

open access: yes, 2016
Primary CD4+ T cells and cell lines differ in their permissiveness to HIV infection. Impaired innate immunity may contribute to this different phenotype. We used transcriptome profiling of 1503 innate immunity genes in primary CD4+ T cells and permissive
Ciuffi, A.   +5 more
core   +4 more sources

Crosstalk Between Gut Microbiota and Innate Immunity and Its Implication in Autoimmune Diseases

open access: yesFrontiers in Immunology, 2020
The emerging concept of microbiota contributing to local mucosal homeostasis has fueled investigation into its specific role in immunology. Gut microbiota is mostly responsible for maintaining the balance between host defense and immune tolerance ...
Yu-hao Jiao   +3 more
semanticscholar   +1 more source

Livestock abundance predicts vampire bat demography, immune profiles, and bacterial infection risk [PDF]

open access: yes, 2018
Human activities create novel food resources that can alter wildlife–pathogen interactions. If resources amplify or dampen, pathogen transmission probably depends on both host ecology and pathogen biology, but studies that measure responses to ...
Altizer, Sonia   +13 more
core   +3 more sources

Metabolomic Profiling Reveals Distinct and Mutual Effects of Diet and Inflammation in Shaping Systemic Metabolism in Ldlr−/− Mice

open access: yesMetabolites, 2020
Changes in modern dietary habits such as consumption of Western-type diets affect physiology on several levels, including metabolism and inflammation. It is currently unclear whether changes in systemic metabolism due to dietary interventions are long ...
Mario A. Lauterbach   +2 more
doaj   +1 more source

MLKL-Driven Inflammasome Activation and Caspase-8 Mediate Inflammatory Cell Death in Influenza A Virus Infection

open access: yesmBio, 2023
Influenza A virus (IAV) triggers multiple programmed cell death pathways, including MLKL-dependent necroptosis, caspase-8-dependent apoptosis, and caspase-1-dependent pyroptosis in myeloid cells.
Xuqiu Lei   +3 more
doaj   +1 more source

Notch, RORC and IL-23 signals cooperate to promote multi-lineage human innate lymphoid cell differentiation

open access: yesNature Communications, 2022
Innate lymphoid cells (ILC) are effector cells that rapidly respond to immune evading stimuli, and despite their functional diversity arise from common precursors.
Carys A. Croft   +9 more
doaj   +1 more source

Trained Innate Immunity, Epigenetics, and Covid-19.

open access: yesNew England Journal of Medicine, 2020
Training Innate Immunity A recent study of immunity in mice showed that the innate immune system can be primed to respond to later bacterial infection through a process called epigenetic scarring, ...
A. Mantovani, M. Netea
semanticscholar   +1 more source

Reviewing the effects of food provisioning on wildlife immunity [PDF]

open access: yes, 2018
While urban expansion increasingly encroaches on natural habitats, many wildlife species capitalize on anthropogenic food resources, which have the potential to both positively and negatively influence their responses to infection.
Babayan, Simon A.   +2 more
core   +1 more source

Human plasmacytoid dendritic cells and cutaneous melanoma [PDF]

open access: yes, 2020
The prognosis of metastatic melanoma (MM) patients has remained poor for a long time. However, the recent introduction of effective target therapies (BRAF and MEK inhibitors for BRAFV600-mutated MM) and immunotherapies (anti-CTLA-4 and anti-PD-1) has ...
Bugatti, Mattia   +4 more
core   +2 more sources

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