Results 11 to 20 of about 971,833 (308)

Innate Immunity and Neuroinflammation [PDF]

Mediators of Inflammation, 2013
Inflammation of central nervous system (CNS) is usually associated with trauma and infection. Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be harmful.
Abhishek Shastri, Domenico Marco Bonifati, Uday Kishore   +2 more
openaire   +6 more sources

Synthesis and validation of click-modified of NOD1/2 agonists [preprint] [PDF]

, 2023
This article is a preprint. Preprints are preliminary reports of work that have not been certified by peer review.NOD1 and NOD2 sense small bacterial peptidoglycan fragments often called muropeptides.
Silverman, Neal, Bharadwaj, Ravi, Brown, Ashley, Anonick, Madison V., Grimes, Catherine L., Wodzanowski, Kimberly A., Okuda, Kendi, Mashayekh, Siavash   +7 more
core   +1 more source

The Novel Inducer of Innate Immunity HO53 Stimulates Autophagy in Human Airway Epithelial Cells [PDF]

, 2022
Aroylated phenylenediamines (APDs) are novel modulators of innate immunity with respect to enhancing the expression of antimicrobial peptides and maintaining epithelial barrier integrity.
Myszor, Iwona T., Agerberth, Birgitta, Sigurdsson, Snaevar, Myszor, IT, Eskelinen, E-L, Viktorsdottir, AR, Gudmundsson, GH, Agerberth, B,, Ogmundsdottir, MH, Gudmundsson, Gudmundur H., Ogmundsdottir, Margret Helga, Viktorsdottir, Alexia Ros, Eskelinen, Eeva-Liisa, Sigurdsson, S   +13 more
core   +2 more sources

Foodies of Innate Immunity [PDF]

Journal of Innate Immunity, 2015
Heiko, Herwald, Arne, Egesten
openaire   +3 more sources

Curating the innate immunity interactome [PDF]

, 2010
peer-reviewedBackground: The innate immune response is the first line of defence against invading pathogens and is regulated by complex signalling and transcriptional networks.
Laird, Matthew R, Anastasia Sribnaia, Winsor, Geoffrey L., Lynn, David J, Giselle Ring, Foroushani, Amir K., Laird, Matthew R., Que, Jaimmie, Geoffrey L Winsor, Robert EW Hancock, Sribnaia, Anastasia, Hancock, Robert E.W., Ring, Giselle, Melissa Yau, Fiona SL Brinkman, Calvin Chan, Jaimmie Que, David J Lynn, Brinkman, Fiona S. L., Naseer, Misbah, Matthew R Laird, Yau, Melissa, Lo, Raymond, Raymond Lo, Chan, Calvin, Wee, Kathleen, Winsor, Geoffrey L, Breuer, Karin, Kathleen Wee, Amir K Foroushani, Hancock, R. E. W. (Robert E. W.), Brinkman, Fiona S., Misbah Naseer, Karin Breuer, Lynn, David J.   +34 more
core   +1 more source

InnateDB: systems biology of innate immunity and beyond—recent updates and continuing curation [PDF]

, 2012
peer-reviewedInnateDB (http://www.innatedb.com) is an integrated analysis platform that has been specifically designed to facilitate systems-level analyses of mammalian innate immunity networks, pathways and genes.
Brinkman, Fiona S. L., Laird, Matthew R, Amir K. Foroushani, David J. Lynn, Anastasia Sribnaia, Lynn, David J, Lo, Raymond, Raymond Lo, Foroushani, Amir K., Winsor, Geoffrey L, Breuer, Karin, Chen, Carol, Robert E. W. Hancock, Matthew R. Laird, Carol Chen, Geoffrey L. Winsor, Sribnaia, Anastasia, Hancock, Robert E.W., Karin Breuer, Fiona S. L. Brinkman   +19 more
core   +1 more source

Innate immunity against HIV: a priority target for HIV prevention research. [PDF]

, 2010
This review summarizes recent advances and current gaps in understanding of innate immunity to human immunodeficiency virus (HIV) infection, and identifies key scientific priorities to enable application of this knowledge to the development of novel ...
PAXTON W, ROMARIS M, LINDBLAD E, DONCEL G, BORROW P, Persephone Borrow, Borrow, P, LEHNER T, DE MAGISTRIS MT, Shattock, Robin J., MEDAGLINI, DONATA, Vyakarnam, Annapurna, PATTERSON S, Annapurna Vyakarnam, POLI G, EUROPRISE WORKING GROUP BOGERS W, KIRCHHOFF F, KELLY C, TOWERS G, SILVESTRI G, DEBRE P, Robin J Shattock, Shattock, RJ, SHATTOCK RJ, Vyakarnam Annapurna, Borrow, Persephone, Borrow Persephone, GOODIER M, null null, SPECK R, EUROPRISE Working Group, GEIJTENBEEK T, Vyakarnam, A, Shattock Robin J, WAGNER H., VYAKARNAM A   +35 more
core   +1 more source

Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity [PDF]

, 2023
Cytosolic innate immune sensing is critical for protecting barrier tissues. NOD1 and NOD2 are cytosolic sensors of small peptidoglycan fragments (muropeptides) derived from the bacterial cell wall.
Nandy, Anubhab, Grimes, Catherine Leimkuhler, Kanneganti, Thirumala-Devi, Bharadwaj, Ravi, Wodzanowski, Kimberly A, Atukorale, Prabhani U, Orzalli, Megan H, Lusi, Christina F, Okuda, Kendi, Nagar, Abhinit, Anonick, Madison V, Silverman, Neal, Subbarao, Malireddi, Paik, Donggi, Kane, Griffin I, Monahan, Amanda, Brown, Ashley R, Goldman, William E, Mashayekh, Siavash   +18 more
core   +1 more source

'Towards a Conceptual Framework for Innate Immunity' [PDF]

, 2005
Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity.
Aickelin, Uwe, Aickelin, U, Twycross, J, Uwe Aickelin, Jamie Twycross, Twycross, Jamie   +5 more
core   +1 more source

Role of metabolic reprogramming in pulmonary innate immunity and Its impact on lung diseases [PDF]

, 2019
Lung innate immunity is the first line of defence against inhaled allergens, pathogens and environmental pollutants. Cellular metabolism plays a key role in innate immunity.
Mumby, Sharon, Bhavsar, Pankaj K, Chung, Kian Fan, Xu, Bingling, Hui, Christopher Kim Ming, Michaeloudes, Charalambos, Adcock, Ian M   +6 more
core   +1 more source