Results 31 to 40 of about 1,017,988 (308)

The role of BRI1-associated kinase 1 (BAK1) in the regulation of plant innate immunity : functional and genetic characterization of BAK1 overexpression in Arabidopsis thaliana [PDF]

open access: yes, 2014
The role of BRI1-ASSOCIATED KINASE 1 (BAK1) in the regulation of plant innate immunity: functional and genetic characterization of BAK1 overexpression in Arabidopsis thaliana SUMMARY BAK1 (BRI1-ASSOCIATED KINASE 1) is an intensively studied member ...
Kiss-Papp, Márta
core   +1 more source

The Epitranscriptome and Innate Immunity [PDF]

open access: yesPLOS Genetics, 2015
Our knowledge of the variety and abundances of RNA base modifications is rapidly increasing. Modified bases have critical roles in tRNAs, rRNAs, translation, splicing, RNA interference, and other RNA processes, and are now increasingly detected in all types of transcripts.
O'Connell, Mary   +2 more
openaire   +4 more sources

In vivo detection of lamellocytes in Drosophila melanogaster. [PDF]

open access: yes, 2009
Drosophila has recently become a powerful model organism for studies of innate immunity. The cellular elements of innate immunity in Drosophila, the hemocytes, have been characterized by morphological criteria, molecular markers, and cell-type-specific ...
Laurinyecz, Barbara   +5 more
core   +1 more source

Naturally derived cytokine peptides limit virus replication and severe disease during influenza A virus infection

open access: yesClinical & Translational Immunology, 2023
Objectives Novel host‐targeted therapeutics could treat severe influenza A virus (IAV) infections, with reduced risk of drug resistance. LAT8881 is a synthetic form of the naturally occurring C‐terminal fragment of human growth hormone.
Christopher M Harpur   +7 more
doaj   +1 more source

A Nutrition-Longevity Tradeoff Enforced by Innate Immunity

open access: yes, 2020
Dietary restriction (DR) extends lifespan in multiple animal species, but the underlying molecular mechanisms remain poorly understood. A recent study published in Cell Metabolism by Wu et al.
Goswamy, Debanjan   +2 more
core   +1 more source

Expression and Localization of Paneth Cells and Their α-Defensins in the Small Intestine of Adult Mouse

open access: yesFrontiers in Immunology, 2020
Paneth cells contribute to intestinal innate immunity by sensing bacteria and secreting α-defensin. In Institute of Cancer Research (ICR) mice, α-defensin termed cryptdin (Crp) in Paneth cells consists of six major isoforms, Crp1 to 6.
Kiminori Nakamura   +9 more
doaj   +1 more source

An ocular Th1 immune response promotes corneal nerve damage independently of the development of corneal epitheliopathy

open access: yesJournal of Neuroinflammation, 2023
Proper sight is not possible without a smooth, transparent cornea, which is highly exposed to environmental threats. The abundant corneal nerves are interspersed with epithelial cells in the anterior corneal surface and are instrumental to corneal ...
Alexia Vereertbrugghen   +10 more
doaj   +1 more source

Adaptive immunity in invertebrates: a straw house without a mechanistic foundation [PDF]

open access: yes, 2007
Recently claims have been made for radical new insights in the field of invertebrate immunology that involve memory, specificity and/or maternal transfer of immunocompetence.
Smith, Valerie J., Hauton, Chris
core   +1 more source

Aging and Innate Immunity [PDF]

open access: yesImmunity, 2006
Adaptive immunity undergoes severe deterioration with age and represents the main problem in the elderly. However, evidence accumulated over the last decade supports the hypothesis that aging also has a profound impact on innate immunity, which in turn markedly impacts the health and longevity of older people.
Solana, Rafael   +2 more
openaire   +2 more sources

Targeting RIP Kinases in Chronic Inflammatory Disease

open access: yesBiomolecules, 2021
Chronic inflammatory disorders are characterised by aberrant and exaggerated inflammatory immune cell responses. Modes of extrinsic cell death, apoptosis and necroptosis, have now been shown to be potent drivers of deleterious inflammation, and mutations
Mary Speir   +4 more
doaj   +1 more source

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