Results 51 to 60 of about 269,683 (272)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Structure of the earth’s topmost inner core from seismic waveform inversion [PDF]

open access: yes, 2017
The Earth’s solid inner core was formed from crystallization of liquid iron in the fluid outer core as the Earth slowly cools. The understanding of the structure of the inner core, combined with high pressure and temperature experiments at core condition,
Jin, Jing
core  

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Neutron star mergers chirp about vacuum energy

open access: yesJournal of High Energy Physics, 2018
Observations of gravitational waves from neutron star mergers open up novel directions for exploring fundamental physics: they offer the first access to the structure of objects with a non-negligible contribution from vacuum energy to their total mass ...
Csaba Csáki   +4 more
doaj   +1 more source

Electronic-structure calculations for nonisothermal warm dense matter

open access: yesPhysical Review Research, 2020
Warm dense matter (WDM) is an exotic state of matter that is inherently difficult to model theoretically, due to the fact that the thermal Coulomb coupling and quantum effects are comparable in magnitude and must be treated on equal footing, foregoing ...
John Jasper Bekx   +3 more
doaj   +1 more source

Synthesis, Characterization, and NH3-SCR Catalytic Performance of Fe-Modified MCM-36 Intercalated with Various Pillars

open access: yesMolecules, 2023
Two series of MCM-36 zeolites intercalated with various pillars and modified with iron were synthesized, analyzed with respect to their physicochemical properties, and tested as catalysts for the NH3-SCR process.
Agnieszka Szymaszek-Wawryca   +3 more
doaj   +1 more source

Molecular biology of hearing

open access: yes, 2012
The inner ear is our most sensitive sensory organ and can be subdivided into three functional units: organ of Corti, stria vascularis and spiral ganglion.
Diensthuber, M   +3 more
core   +1 more source

Analysing the Relationship between Mechanical Properties and Inner Structure of LLDPE Virgin Film for Optimizing Extrusion Condition

open access: yes, 2023
In this study, we investigated the mechanical properties and inner structure of the films of linear low-density polyethylene (LLDPE) It was re-pelletized by a twin-screw extruder equipped with and without a molten-resin reservoir (MRR) with different ...
Yosuke Matsukuma   +3 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

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