Results 71 to 80 of about 1,282,933 (259)

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Application of New Structure on Power House with Large Variable Tailwater in Karst Area

open access: yesRenmin Zhujiang, 2020
The power house behind Jiayan dam in Guizhou Province is located in Karst area.Affectedby the backwater effect of underground river, the tailwater head of power plant reaches 44.92 m,and the retaining height is equivalent to a gravity dam in medium ...
GUAN Zhibao   +3 more
doaj  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Abundance and diversity patterns of the sessile macrobenthic community associated with environmental gradients in Vitória Harbor, southeastern Brazil</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Zoologia (Curitiba)</i>, 2011 </span><br><span class="r_content">Harbor terminals and urban sewage effluents affect the composition and distribution of epibenthic organisms. In this study, we hypothesized that the benthic community structure at the Vitoria Harbor changes spatially in a ~3 km scale, and that these ...</span><br><span class="r_sub"><i>Ilana Rosental Zalmon<span id="ma_5" style="display:none">, Werther Krohling, Carlos Eduardo Leite Ferreira</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_5')">+2 more</a></small></i></span><br><small><a href="https://doaj.org/article/b7606b917f75418593d6fd18dc7114fc" target="_blank" rel="nofollow" title="doaj.org/article/b7606b917f75418593d6fd18dc7114fc">doaj</a> </small>   <div id="more_5" style="display:none"><a href="/sci_redir.php?doi=10.1590%2FS1984-46702011000500012" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1590/S1984-46702011000500012'); alert('Copied the doi');">copy doi</a> <small>(10.1590/S1984-46702011000500012)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_5')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1074/jbc.m115.697789" target="_blank" rel="nofollow">Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction.</a> <b><a href="https://core.ac.uk/download/46975705.pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16">, 2016 </span><br><span class="r_content">The intrinsic apoptosis pathway occurs through the release of mitochondrial cytochrome c to the cytosol, where it promotes activation of the caspase family of proteases.</span><br><span class="r_sub"><i>Christian, Thomas<span id="ma_6" style="display:none">, Hou, Ya-Ming, Liu, Cuiping, Stonestrom, Aaron J, Takase, Ryuichi, Yang, Xiaolu, Yong, Jeongsik</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_6')">+6 more</a></small></i></span><br><small><a href="https://core.ac.uk/works/26707059" target="_blank" rel="nofollow" title="core.ac.uk/works/26707059">core</a> </small>   <div id="more_6" style="display:none"><a href="/sci_redir.php?doi=10.1074%2Fjbc.m115.697789" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="https://jdc.jefferson.edu/cgi/viewcontent.cgi?article=1104&context=bmpfp" target="_blank" rel="nofollow" title="jdc.jefferson.edu/cgi/viewcontent.cgi?article=1104&context=bmpfp">jdc.jefferson.edu</a><br> <a href="javascript:navigator.clipboard.writeText('10.1074/jbc.m115.697789'); alert('Copied the doi');">copy doi</a> <small>(10.1074/jbc.m115.697789)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_6')">+2 more sources</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/2211-5463.70184" target="_blank" rel="nofollow">Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>FEBS Open Bio, EarlyView.</i></span><br><span class="r_content">Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...</span><br><span class="r_sub"><i>Wanqiong Li<span id="ma_7" style="display:none">, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_7')">+8 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/2211-5463.70184?mi=2or9o2m&af=R&AllField=inner access structure&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/2211-5463.70184?mi=2or9o2m&af=R&AllField=inner access structure&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small>   <div id="more_7" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F2211-5463.70184" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/2211-5463.70184'); alert('Copied the doi');">copy doi</a> <small>(10.1002/2211-5463.70184)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_7')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1063/1.2402711" target="_blank" rel="nofollow">An Integrated Tracker for STAR</a> <b><a href="https://core.ac.uk/download/44134505.pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16">, 2006 </span><br><span class="r_content">The STAR experiment at the Relativistic Heavy Ion Collider RHIC studies the new state of matter produced in relativistic heavy ion collisions and the spin structure of the nucleon in collisions of polarized protons.</span><br><span class="r_sub"><i>Adams, J<span id="ma_8" style="display:none">, Barnby, Lee, Blyth, CO, Gaillard, Leon, Jones, Peter, Nelson, John, Simon, F, Timmins, Anthony</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_8')">+7 more</a></small></i></span><br><small><a href="https://core.ac.uk/works/1129937" target="_blank" rel="nofollow" title="core.ac.uk/works/1129937">core</a> </small>   <div id="more_8" style="display:none"><a href="/sci_redir.php?doi=10.1063%2F1.2402711" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="http://arxiv.org/abs/physics/0608199" target="_blank" rel="nofollow" title="arxiv.org/abs/physics/0608199">arxiv.org</a><br> <a href="javascript:navigator.clipboard.writeText('10.1063/1.2402711'); alert('Copied the doi');">copy doi</a> <small>(10.1063/1.2402711)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_8')">+2 more sources</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/2211-5463.70185" target="_blank" rel="nofollow">Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>FEBS Open Bio, EarlyView.</i></span><br><span class="r_content">ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...</span><br><span class="r_sub"><i>Sébastien Soubeyrand<span id="ma_9" style="display:none">, Paulina Lau, Ruth McPherson</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_9')">+2 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/2211-5463.70185?mi=2or9o2m&af=R&AllField=inner access structure&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/2211-5463.70185?mi=2or9o2m&af=R&AllField=inner access structure&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small>   <div id="more_9" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F2211-5463.70185" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/2211-5463.70185'); alert('Copied the doi');">copy doi</a> <small>(10.1002/2211-5463.70185)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_9')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1109/ACCESS.2019.2919726" target="_blank" rel="nofollow">A Dispersed Multi-Value Attribute-Based Encryption With Mediated Obfuscation</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>IEEE Access</i>, 2019 </span><br><span class="r_content">The Multi-authority attribute-based encryption (MA-ABE) scheme can provide fine-grained data access control in many management domains monitored by different authorities for the cloud storage system.</span><br><span class="r_sub"><i>Shengzhou Hu, Jiguo Li, Yichen Zhang</i></span><br><small><a href="https://doaj.org/article/a47f4ab6aa8b4ecb85378c4b0ee45533" target="_blank" rel="nofollow" title="doaj.org/article/a47f4ab6aa8b4ecb85378c4b0ee45533">doaj</a> </small>   <div id="more_10" style="display:none"><a href="/sci_redir.php?doi=10.1109%2FACCESS.2019.2919726" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1109/ACCESS.2019.2919726'); alert('Copied the doi');">copy doi</a> <small>(10.1109/ACCESS.2019.2919726)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_10')">+1 more source</a></small><br></div><div class="r"><div style="margin-bottom:2px;overflow:hidden"><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-access_structure/" class="suggestion"onclick="show_loader();"><b>access structure</b></a><br/><a href="/q-outer_access_structure/" class="suggestion"onclick="show_loader();"><b>outer access structure</b></a><br/><a href="/q-metalexicography/" class="suggestion"onclick="show_loader();"><b>metalexicography</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-outer_search_path/" class="suggestion"onclick="show_loader();"><b>outer search path</b></a><br/><a href="/q-inner_search_path/" class="suggestion"onclick="show_loader();"><b>inner search path</b></a><br/><a href="/q-dictionary_accessibility/" class="suggestion"onclick="show_loader();"><b>dictionary accessibility</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"></div></div></div><div class="pagenav"><a href="/q-inner_access_structure/p-7/" rel="nofollow"><b>previous</b></a>   <a href="/q-inner_access_structure/p-6/" rel="nofollow">6</a>  <a href="/q-inner_access_structure/p-7/" rel="nofollow">7</a>  <b>8</b>  <a href="/q-inner_access_structure/p-9/" rel="nofollow">9</a>  <a href="/q-inner_access_structure/p-10/" rel="nofollow">10</a>   <a href="/q-inner_access_structure/p-9/" id="next" rel="nofollow"><b>next</b></a> </div><br></div> </div> <script>document.getElementById('loadingGif').style.display='none';</script><div style="width: 100%; height: 40px; bottom: 0px; background-color: #f5f5f5;"><div style="padding-left: 15px; padding-top: 10px"> <a href="/" rel="nofollow">Home</a> - <a href="/page-about/" rel="nofollow">About</a> - <a href="/page-disclaimer/" rel="nofollow">Disclaimer</a> - <a href="/page-privacy/" rel="nofollow">Privacy</a> </div></div> <link rel="stylesheet" href="//ajax.googleapis.com/ajax/libs/jqueryui/1.11.4/themes/smoothness/jquery-ui.min.css"/> </body> </html>