Results 91 to 100 of about 451,488 (358)
Advanced Science, EarlyView.Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu +12 more
wiley +1 more source
Embryonic cranial cartilage defects in the Fgfr3Y367C/+ mouse model of achondroplasia
The Anatomical Record, EarlyView., 2023 Abstract Achondroplasia, the most common chondrodysplasia in humans, is caused by one of two gain of function mutations localized in the transmembrane domain of fibroblast growth factor receptor 3 (FGFR3) leading to constitutive activation of FGFR3 and subsequent growth plate cartilage and bone defects.
Susan M. Motch Perrine +9 more
wiley +1 more source
Reconstitution of mouse inner ear sensory development from pluripotent stem cells [PDF]
, 2014 Indiana University-Purdue University Indianapolis (IUPUI)The inner ear contains specialized sensory epithelia that detect head movements, gravity and sound.
Koehler, Karl R.
core +1 more source
Advances in Microfluidic Cochlea‐On‐A‐Chip
Advanced Science, EarlyView.This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen +10 more
wiley +1 more source
Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]
, 2017 open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura +6 more
core +2 more sources
Purinergic signaling in the inner ear [PDF]
Hearing Research, 2008 Epithelial cells of the inner ear coordinate their ion transport activity through a number of mechanisms. One important mechanism is the autocrine and paracrine signaling among neighboring cells in the ear via nucleotides, such as adenosine, ATP and UTP.
Daniel C. Marcus, Jun Ho Lee
openaire +4 more sources
Advanced Science, EarlyView.Data from a prospective cohort with 112 auditory brainstem implant users are analyzed. Younger age at implantation (<3 years), less severe inner‐ear malformation (common cavity, cochlear aplasia, and hypoplasia), and more intraoperative eABR evoked electrodes (≥60%) are associated with better hearing and speech outcomes.
Yu Zhang +11 more
wiley +1 more source
Molecular characterization and prospective isolation of human fetal cochlear hair cell progenitors
Nature Communications, 2018 Hearing requires mechanosensitive hair cells in the organ of Corti, which derive from progenitors of the cochlear duct. Here the authors examine human inner ear development by studying key developmental markers and describe organoid cultures from human ...
Marta Roccio +5 more
doaj +1 more source
The shape of the ear canal [PDF]
, 2005 It is proved that the measurement of the acoustic pressure on the ear membrane allows one to determine the shape of the ear $ uniquely.
arxiv +1 more source
Instrument flight to the inner ear [PDF]
Science Robotics, 2017 Image-guided robotic surgery, designed for operating on small structures, is demonstrated for robotic cochlear implantation.
Stefan Weber +16 more
openaire +3 more sources