Results 111 to 120 of about 1,559,915 (394)

Cracking the Valence Code: Patterned Facial Kinematics and Neural Signatures of Emotional Expressions in Mice

Advanced Science, EarlyView.
An AI‐powered system decodes emotional valence from mouse facial expressions, identifying ear dynamics as key indicators. By integrating facial kinematics with synchronized neural recordings, this approach establishes a direct link between behavior and brain activity, advancing automated emotion recognition in animal models.
Yujia Chen, Ruiqing Hou, Zhinan Chen, Junli Lu, Si Chen, Shisheng Xiong, Jianfeng Feng, Trevor W. Robbins, Haitao Yan, Xiao Xiao   +9 more
wiley   +1 more source

A unique radioprotective effect of resolvin E1 reduces irradiation-induced damage to the inner ear by inhibiting the inflammatory response

Radiation Oncology, 2020
Background In addition to the direct effects of irradiation, the induced inflammatory response may play an important role in the damage to the inner ear caused by radiotherapy for the treatment of head and neck cancers.
Jie Zhang, Anting Xu, Tingting Niu, Chengcheng Liu, Yongju Zhang, Tao Li, Jihua Wang, Yongjing Wang, Dianshui Sun   +8 more
doaj   +1 more source

Targeting Neutrophil/Eosinophil Extracellular Traps by Aptamer‐Functionalized Nanosheets to Overcome Recalcitrant Inflammatory Disorders

Advanced Science, EarlyView.
In this study, C‐TAH, as multifunctional nanosheets, is developed with tannic acid and histone aptamer coverage. C‐TAH displays mild cytotoxicity, robust dsDNA and NETs/EETs binding efficiency, and potent antioxidant and antibacterial ability in vitro. C‐TAH treatment ameliorates dysregulated inflammation and restores hearing function in animal models,
Yongqiang Xiao, Xinyue Wang, Ming Liu, Xiao Fu, Nanfeng Zhang, Wenqing Yang, Junyi Ge, Yangyang Li, Duan Ma, Jing Ma, Weiping Wen, Dongdong Ren, Tianyu Zhang, Zhaoxu Tu   +13 more
wiley   +1 more source

Gfi1Cre mice have early onset progressive hearing loss and induce recombination in numerous inner ear non-hair cells

Scientific Reports, 2017
Studies of developmental and functional biology largely rely on conditional expression of genes in a cell type-specific manner. Therefore, the importance of specificity and lack of inherent phenotypes for Cre-driver animals cannot be overemphasized.
Maggie S. Matern, Sarath Vijayakumar, Zachary Margulies, B. Milon, Yang Song, Ran Elkon, Xiaoyu Zhang, Sherri M. Jones, R. Hertzano   +8 more
semanticscholar   +1 more source

Sequence similarity between stereocilin and otoancorin points to a unified mechanism for mechanotransduction in the mammalian inner ear [PDF]

, 2011
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Jovine, Luca, Park, Jong, Wassarman, Paul M   +2 more
core   +3 more sources

Additive Manufactured Magnetoelectric Wireless Retainer as the Periodontal Remodeler for Post‐Orthodontic Tissue Reconstruction and Relapse‐Inhibition

Advanced Science, EarlyView.
Orthodontic relapse persists as a 120‐year challenge, as traditional retainers fail to remodel tissue, causing lifelong dependence. This study demonstrates a flexible magnetoelectric retainer (FMOR) enabling wireless periodontal remodeling. FMOR cues shift periodontal ligament cell (PDLC) paracrine signaling, promoting M2 macrophages, osteogenic ...
Haoqi Lei, Jiwei Sun, Peng Chen, Li Hu, Xin Zhou, Shiqiang Gong, Qingming Tang, Xiaoqing Han, Lili Chen, Bin Su   +9 more
wiley   +1 more source

Chaotic Dynamics Enhance the Sensitivity of Inner Ear Hair Cells [PDF]

, 2019
Hair cells of the auditory and vestibular systems are capable of detecting sounds that induce sub-nanometer vibrations of the hair bundle, below the stochastic noise levels of the surrounding fluid.
Bozovic, Dolores, Faber, Justin
core   +1 more source

Harmonic response of the organ of corti: results for wave dispersion [PDF]

, 2011
Inner ear is a remarkable multiphysical system and its modelling is a great challenge. The approach used in this paper aims to reproduce physic with a realistic description of the radial cross section of the cochlea. A 2D‐section of the organ of Corti is
Foucaud, Simon, Gourinat, Yves, Michon, Guilhem, Morlier, Joseph   +3 more
core   +1 more source

Engineered Anti‐Senescence Trachea With Post‐Transplanted Regenerative Homeostasis

Advanced Science, EarlyView.
Bioengineered trachea undergoes post‐transplanted senescence, which is found in this study for the first time. Hebe‐ET is designed with dual anti‐senescence strategies: fiber‐film scaffold in cartilage rings for close‐packed cell interaction, and quercetin‐loaded fibrous rings for immune modulation.
Ziyin Pan, Hai Tang, Lanlan Wang, Qingfeng Bai, Yi Chen, Runfeng Cao, Weikang Lin, Lei Wang, Yulong Hu, Guofang Zhao, Minglei Yang, Weiyan Sun, Kun Zhang, Dawei Li, Chang Chen   +14 more
wiley   +1 more source

SOX2 is required for inner ear neurogenesis

Scientific Reports, 2017
Neurons of the cochleovestibular ganglion (CVG) transmit hearing and balance information to the brain. During development, a select population of early otic progenitors express NEUROG1, delaminate from the otocyst, and coalesce to form the neurons that ...
A. Steevens, Danielle L. Sookiasian, J. Glatzer, A. Kiernan   +3 more
semanticscholar   +1 more source