Results 231 to 240 of about 451,488 (358)

A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T‐tubule pH regulation

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Disruption of extracellular pH and proton‐sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a zebrafish transgenic line that ubiquitously expresses the ratiometric pH‐sensitive fluorescent protein pHluorin2, tethered to
Leif R. Neitzel   +5 more
wiley   +1 more source

Living in the edge: demographic responses driven by density‐dependence and pulsed resources in a hibernating mammal

open access: yesEcography, EarlyView.
Populations at the edge of a species' distribution often encounter more challenging environmental conditions than those at the core, requiring unique adaptations and strategies. However, the demographic processes driving these populations remain poorly understood.
Daniel Oro   +4 more
wiley   +1 more source

Activation and inhibition of Notch signaling facilitate proliferative regeneration of sensory cells in adult mice

open access: yesEye &ENT Research, EarlyView.
Abstract Due to the limited regenerative capacity in adult mammals, the loss of vestibular hair cells (HCs) leads to balance disorders. In this study, we chronologically reprogrammed adult vestibular supporting cells (SCs) via bimodal regulation of Notch signaling, mimicking dynamic changes in Notch signaling during inner ear development. We found that
Shan Zeng   +5 more
wiley   +1 more source

Applications and Challenges of Auditory Brain‐Computer Interfaces in Objective Auditory Assessments for Pediatric Cochlear Implants

open access: yesExploration, EarlyView.
Auditory brain‐computer interface connects the brain with external devices and decodes neural signals related to auditory perception. Time‐domain and frequency‐domain analyses are commonly used to identify biomarkers associated with auditory rehabilitation, such as cortical auditory evoked potentials and mismatch negativity.
Qi Zheng   +6 more
wiley   +1 more source

Drug selection for inner ear therapy. [PDF]

open access: yesFront Pharmacol
Salt AN, Turner JG.
europepmc   +1 more source

Harnessing Jasminum Bioactive Compounds: Updated Insights for Therapeutic and Food Preservation Innovations

open access: yesFood Frontiers, EarlyView.
Jasminum bioactives improve food preservation by providing antimicrobial and antioxidant effects, especially when incorporated into active packaging, edible films, and nanoformulations that enhance stability and controlled release. They also offer many pharmacological benefits, including anti‐inflammatory, neuroprotective, and wound‐healing properties.
Antonio Rescigno   +17 more
wiley   +1 more source

Crosstalk Signaling Between the Epithelial and Non-Epithelial Compartments of the Mouse Inner Ear. [PDF]

open access: yesJ Assoc Res Otolaryngol
David AP   +8 more
europepmc   +1 more source

The Aquaporin‐4 Expression and Localization in the Olfactory Epithelium Modulate the Odorant‐Evoked Responses and Olfactory‐Driven Behavior

open access: yesGlia, EarlyView.
ABSTRACT Aquaporin‐4 (AQP4) is a water‐selective channel expressed in glial cells throughout the central nervous system (CNS). It serves as the primary water channel in the neuropil and plays roles in physiological functions, including regulating water homeostasis by adjusting cell volume and modulating neuronal activity. Different isoforms of AQP4 are
Donatella Lobraico   +8 more
wiley   +1 more source

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